HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30266805, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Hs			1 383
+	Hs
		1119083 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		HECW2_HUMAN (2-325): 2.21e-42: 160: 17.63
+	Hs
		1119026 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Hs
		125503 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP2_HUMAN (45-319): 1.29e-33: 134: 15.85
+	Hs
		1118983 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47
+	Hs
		1119035 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		MAGI1_HUMAN (170-306): 1.6e-29: 122: 26.55
+	Hs
		1119076 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		1119052 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP1_HUMAN (3-322): 5.63e-29: 120: 15.12
+	Hs
		808151 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NEDD4_HUMAN (42-307): 3.99e-20: 94.4: 14.84
+	Hs
		1119034 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NED4L_HUMAN (151-312): 1.2e-09: 62.1: 18.07
+	Hs
		125569 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		WWP2_HUMAN (45-319): 1.29e-33: 134: 15.85
+	Hs
		1132674 FKB15_HUMAN (184-1080): 4.84e-41: 166: 14.92		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		1199783 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		MAGI2_HUMAN (148-276): 1.51e-30: 125: 23.94
+	Hs
		1220065 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47
+	Hs
		1220103 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47
+	Hs
		1222264 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		MAGI1_HUMAN (170-306): 1.6e-29: 122: 26.55
+	Hs
		1222274 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		1349059 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		1222267 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		WWP1_HUMAN (3-322): 5.63e-29: 120: 15.12
+	Hs
		808183 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NEDD4_HUMAN (42-307): 3.99e-20: 94.4: 14.84
+	Hs
		1222263 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NED4L_HUMAN (151-312): 1.2e-09: 62.1: 18.07