HitPredict

Interactor 1: DHB12 (Q53GQ0)
Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1)
Gene: HSD17B12

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	25416956, 32814053
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 312 Hs			1 589
+	Hs
		1121034 DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1355416 DHRS7_HUMAN (55-232): 4.21e-15: 76.6: 32.43		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		924023 DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924353 DHB11_HUMAN (29-256): 1.18e-62: 202: 29.06		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924075 DHB11_HUMAN (29-256): 1.18e-62: 202: 29.06		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924223 DHRS7_HUMAN (55-232): 4.21e-15: 76.6: 32.43		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68