Protein: THUM3
tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3)

Gene: THUM3, THUMPD3
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q9BV44

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016423 - tRNA (guanine) methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1313480

TR112
Multifunctional methyltransferase subunit TRM112-like protein

5

3

Small-scale

0.928

High

1287634

ZN501
Zinc finger protein 501

3

0

High-throughput

0.638

High

1263863

ACO11
Acyl-coenzyme A thioesterase 11

3

0

High-throughput

0.634

High

1192570

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

2

1

High-throughput

0.628

High

260670

AVIL
Advillin

2

0

High-throughput

0.602

High

272384

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

2

0

High-throughput

0.602

High

273479

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.602

High

844220

FXR2
RNA-binding protein FXR2

2

0

High-throughput

0.602

High

905401

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

2

0

High-throughput

0.602

High

1103446

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

2

0

High-throughput

0.602

High

1313473

NSUN3
tRNA

2

0

High-throughput

0.602

High

1313482

PUS1
Pseudouridylate synthase 1 homolog

2

0

High-throughput

0.602

High

1018028

GRSF1
G-rich sequence factor 1

2

2

High-throughput

0.584

High

1157143

ESRP1
Epithelial splicing regulatory protein 1

2

2

High-throughput

0.574

High

1204255

MICU3
Calcium uptake protein 3, mitochondrial

2

1

High-throughput

0.574

High

1308646

MICU1
Calcium uptake protein 1, mitochondrial

2

1

High-throughput

0.574

High

228553

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

243584

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.536

High

159770

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.513

High

277350

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

278657

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

611328

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.513

High

958236

RBM3
RNA-binding protein 3

1

0

High-throughput

0.513

High

1039164

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.513

High

1241397

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.513

High

1259401

GRK7
Rhodopsin kinase GRK7

1

0

High-throughput

0.513

High

1284788

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1313472

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1313475

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.513

High

1313476

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

1313481

CTND2
Catenin delta-2

1

0

High-throughput

0.513

High

295205

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

1058286

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.479

High

1171510

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1313471

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1313479

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

134189

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

High-throughput

0.458

High

323078

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

347775

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

780025

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1025533

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1071693

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1313474

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1313477

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

652131

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

1130535

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1107840

EDRF1
Erythroid differentiation-related factor 1

2

0

High-throughput

0.328

High

212070

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

1

0

High-throughput

0.279

Low

945335

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

985255

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.279

Low

1030755

SLAF1
Signaling lymphocytic activation molecule

1

0

High-throughput

0.279

Low

1078256

EFNB3
Ephrin-B3

1

0

High-throughput

0.279

Low

1232960

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1286808

ZN653
Zinc finger protein 653

1

0

High-throughput

0.279

Low

1302158

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

1313469

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

0

High-throughput

0.279

Low

1313470

GTSFL
Gametocyte-specific factor 1-like

1

0

High-throughput

0.279

Low

1313478

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.279

Low

321429

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

0

High-throughput

0.265

Low

385451

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

533059

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.249

Low

553601

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

787175

RHG25
Rho GTPase-activating protein 25

1

0

High-throughput

0.249

Low

990652

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.249

Low

1029816

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1284628

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1289996

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.249

Low

484905

GAGE1
G antigen 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024