HitPredict

Interactor 1: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 565 Hs			1 126
+	Hs
		918411 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1087318 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707705 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		707807 UBP3_HUMAN (105-563): 1.97e-121: 369: 19.73		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918801 UBP3_HUMAN (105-563): 1.97e-121: 369: 19.73		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1231220 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		1087489 UBP22_HUMAN (123-560): 1.99e-114: 351: 17.39		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707794 UBP22_HUMAN (123-560): 1.99e-114: 351: 17.39		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		707665 UBP51_HUMAN (123-559): 3.6e-109: 344: 15.96		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		271037 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		777048 UBP8_HUMAN (177-564): 2.41e-101: 332: 19.80		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707785 UBP21_HUMAN (223-560): 2.89e-97: 308: 18.85		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Sc
		355943 UBP8_YEAST (80-552): 2.01e-107: 331: 16.80		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Dm
		355274 UBP7_DROME (66-560): 5.75e-92: 307: 14.42		H2B_DROME (36-126): 6.89e-47: 148: 94.51
+	Sc
		355547 UBP8_YEAST (80-552): 2.01e-107: 331: 16.80		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Hs
		905383 UBP46_HUMAN (201-556): 1.61e-90: 284: 19.31		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		905394 UBP46_HUMAN (201-556): 1.61e-90: 284: 19.31		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		259286 UBP12_HUMAN (209-556): 5.21e-90: 283: 18.92		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		1087411 UBP42_HUMAN (225-557): 2.68e-78: 270: 24.42		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		241654 UBP36_HUMAN (225-564): 4.97e-62: 223: 20.69		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41