HitPredict

Interactor 1: KLH22 (Q53GT1)
Kelch-like protein 22
Gene: KLHL22

Interactor 2: KLH20 (Q9Y2M5)
Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X)
Gene: KLHL20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, Kelch_1~Kelch_1, Kelch_1~Kelch_3, Kelch_1~Kelch_6
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 634
Hs

1 609
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024