Interactor 1: BOREA (Q53HL2)
Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)
Gene: CDCA8

Interactor 2: INCE (Q9NQS7)
Inner centromere protein
Gene: INCENP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 18946085, 15249581, 17099693, 17956729, 16571674, 19951914, 16239925, 20739936
Identification Methods affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains INCENP_N~Nbl1_Borealin_N
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000775 - chromosome, centromeric region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 11 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 280
Hs

1 918
+ Xl
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024