HitPredict

Interactor 1: JIP4 (Q58A65)
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)
Gene: Spag9

Interactor 2: MK08 (Q91Y86)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1)
Gene: Mapk8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15767678
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019894 - kinesin binding GO:0030335 - positive regulation of cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1321 Mm			1 384
+	Hs
		229640 JIP4_HUMAN (1-1321): 0: 755: 96.52		MK08_HUMAN (1-378): 4.15e-147: 424: 100.00
+	Hs
		229677 JIP4_HUMAN (1-1321): 0: 755: 96.52		MK14_HUMAN (4-366): 3.96e-127: 371: 45.90
+	Hs
		800848 JIP3_HUMAN (1-1321): 0: 701: 53.48		MK08_HUMAN (1-378): 4.15e-147: 424: 100.00
+	Mm
		814047 JIP4_MOUSE (1-1321): 0: 753: 100.00		MK14_MOUSE (4-366): 1.66e-127: 372: 45.90
+	Hs
		864879 JIP3_HUMAN (1-1321): 0: 701: 53.48		MK10_HUMAN (1-382): 9.87e-146: 422: 91.62
+	Hs
		800962 JIP3_HUMAN (1-1321): 0: 701: 53.48		MK09_HUMAN (1-380): 1.24e-143: 416: 83.42
+	Mm
		1265205 JIP3_MOUSE (10-1321): 0: 673: 55.28		MK08_MOUSE (1-384): 1.23e-147: 424: 100.00
+	Mm
		1143154 JIP3_MOUSE (10-1321): 0: 673: 55.28		MK10_MOUSE (1-382): 3.81e-145: 421: 91.10
+	Mm
		1322366 JIP3_MOUSE (10-1321): 0: 673: 55.28		MK09_MOUSE (1-380): 1.59e-142: 413: 84.74
+	Hs
		229628 JIP4_HUMAN (1-1321): 0: 755: 96.52		MK01_HUMAN (20-359): 8.67e-84: 261: 42.98
+	Mm
		926440 JIP3_MOUSE (10-1321): 0: 673: 55.28		MK01_MOUSE (20-359): 9.09e-84: 261: 42.98
+	Ce
		712388 JIP_CAEEL (15-1316): 2.91e-143: 468: 31.20		JNK1_CAEEL (1-367): 3.06e-131: 386: 68.02
+	Hs
		960128 MYH2_HUMAN (2-924): 1.42e-35: 150: 10.93		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23
+	Hs
		528401 MYH8_HUMAN (246-1002): 4.89e-27: 122: 9.72		CDK2_HUMAN (23-329): 1.01e-133: 386: 33.23
+	Hs
		625176 MYH9_HUMAN (293-971): 1.08e-24: 114: 8.96		CDK2_HUMAN (23-329): 1.01e-133: 386: 33.23
+	Hs
		528405 MYH8_HUMAN (246-1002): 4.89e-27: 122: 9.72		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23
+	Hs
		522542 MYH1_HUMAN (246-1001): 7.28e-26: 118: 9.21		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23
+	Hs
		528368 MYH6_HUMAN (246-1001): 1.41e-25: 117: 9.00		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23
+	Hs
		522604 MYH7_HUMAN (1-695): 6.54e-24: 112: 10.00		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23
+	Hs
		502908 MYH3_HUMAN (358-966): 1.4e-19: 98: 9.51		CDK3_HUMAN (23-323): 8.18e-128: 371: 33.23