HitPredict

Interactor 1: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1

Interactor 2: BICD2 (Q8TD16)
Protein bicaudal D homolog 2 (Bic-D 2)
Gene: BICD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	28718761, 11483508, 22956769, 25512093
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0051959 - dynein light intermediate chain binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 4646 Hs			1 824
+	Hs
		1123920 DYHC1_HUMAN (1-4646): 0: 4193: 100.00		GRDN_HUMAN (277-819): 1.09e-16: 87.5: 12.14
+	Hs
		1124074 DYHC1_HUMAN (1-4646): 0: 4193: 100.00		DAPLE_HUMAN (7-536): 5.61e-11: 68.8: 20.00
+	Hs
		157362 DYHC1_HUMAN (1-4646): 0: 4193: 100.00		CTRO_HUMAN (17-823): 1.28e-10: 67.6: 15.51
+	Dm
		597825 DYHC_DROME (23-4645): 0: 3966: 71.40		BICD_DROME (15-823): 6.29e-71: 250: 37.82
+	Hs
		1350383 DYH5_HUMAN (13-4644): 0: 3600: 21.83		BICD2_HUMAN (1-824): 8.18e-55: 205: 100.00
+	Mm
		1037843 DYH5_MOUSE (13-4644): 0: 3635: 22.04		MYH6_MOUSE (1-657): 5.47e-28: 124: 11.25
+	Hs
		772920 DYH5_HUMAN (13-4644): 0: 3600: 21.83		MYH9_HUMAN (530-824): 3.44e-10: 66.3: 12.75
+	Hs
		773008 DYH6_HUMAN (931-4645): 0: 3457: 25.70		MYH9_HUMAN (530-824): 3.44e-10: 66.3: 12.75
+	Hs
		157626 DYHC2_HUMAN (250-4646): 0: 2836: 25.65		CTRO_HUMAN (17-823): 1.28e-10: 67.6: 15.51
+	Hs
		157529 DYH12_HUMAN (3846-4645): 0: 868: 21.83		CTRO_HUMAN (17-823): 1.28e-10: 67.6: 15.51