Interactor 1: CENPW (Q5EE01)
Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein)
Gene: CENPW

Interactor 2: CENPT (Q96BT3)
Centromere protein T (CENP-T) (Interphase centromere complex protein 22)
Gene: CENPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 33961781, 25775162, 23926101, 19533040, 22304917
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, pull down, two hybrid, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~CENP-W
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000939 - inner kinetochore
GO:0003677 - DNA binding
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 88
Hs

1 561
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024