HitPredict

Interactor 1: G5EEL3 (G5EEL3)
Nuclear Hormone Receptor family
Gene: nhr-70

Interactor 2: MEC3 (P09088)
Mechanosensory protein 3
Gene: mec-3

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 389 Ce			1 321
+	Ce
		478999 Q95QB3_CAEEL (1-389): 7.74e-102: 308: 36.74		MEC3_CAEEL (1-321): 1.78e-67: 215: 100.00
+	Ce
		478983 Q21372_CAEEL (11-383): 1.71e-90: 280: 25.00		MEC3_CAEEL (1-321): 1.78e-67: 215: 100.00
+	Ce
		112619 NH114_CAEEL (2-387): 7e-87: 271: 18.53		MEC3_CAEEL (1-321): 1.78e-67: 215: 100.00
+	Hs
		833908 HNF4A_HUMAN (2-387): 3.12e-99: 304: 22.28		ISL1_HUMAN (14-312): 2.44e-45: 159: 22.52
+	Hs
		522813 COT1_HUMAN (2-386): 6.41e-98: 299: 18.96		ISL1_HUMAN (14-312): 2.44e-45: 159: 22.52
+	Ce
		112620 NH114_CAEEL (2-387): 7e-87: 271: 18.53		LIN11_CAEEL (3-289): 2.93e-50: 173: 30.31
+	Hs
		253021 ESR2_HUMAN (2-387): 5.92e-80: 256: 17.86		LMX1B_HUMAN (1-316): 2.18e-55: 187: 22.15
+	Hs
		395803 ESR1_HUMAN (1-387): 4.1e-88: 279: 19.19		ISL1_HUMAN (14-312): 2.44e-45: 159: 22.52
+	Hs
		395812 ESR1_HUMAN (1-387): 4.1e-88: 279: 19.19		LMO4_HUMAN (10-145): 2.34e-39: 138: 21.43
+	Hs
		395682 ESR1_HUMAN (1-387): 4.1e-88: 279: 19.19		PAXI_HUMAN (2-208): 1.11e-30: 123: 15.79
+	Hs
		878525 ESR2_HUMAN (2-387): 5.92e-80: 256: 17.86		PAXI_HUMAN (2-208): 1.11e-30: 123: 15.79
+	Ce
		478997 Q86PI8_CAEEL (11-89): 7.33e-20: 90.9: 45.57		MEC3_CAEEL (1-321): 1.78e-67: 215: 100.00
+	Ce
		628568 Q86PI8_CAEEL (11-89): 7.33e-20: 90.9: 45.57		LIN11_CAEEL (3-289): 2.93e-50: 173: 30.31