HitPredict

Interactor 1: Q5JC29 (Q5JC29)
Epidermal growth factor receptor pathway substrate 15 isoform B
Gene: Eps15

Interactor 2: Q66HM2 (Q66HM2)
AP-2 complex subunit alpha
Gene: Ap2a2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17762867
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030122 - AP-2 adaptor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 792 Rn			1 939
+	Hs
		302112 EPS15_HUMAN (1-788): 4.17e-139: 435: 88.34		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Mm
		567515 EPS15_MOUSE (1-777): 4.77e-126: 400: 94.34		AP2A2_MOUSE (1-939): 0: 889: 99.57
+	Hs
		321504 EPS15_HUMAN (1-788): 4.17e-139: 435: 88.34		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Rn
		88764 Q5JC29_RAT (1-792): 1.51e-137: 427: 100.00		D3ZUY8_RAT (1-939): 0: 836: 81.25
+	Hs
		302221 EP15R_HUMAN (1-790): 2.69e-95: 318: 41.01		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Hs
		321661 EP15R_HUMAN (1-790): 2.69e-95: 318: 41.01		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Rn
		88768 ITSN1_RAT (9-776): 1.45e-80: 285: 16.87		D3ZUY8_RAT (1-939): 0: 836: 81.25
+	Hs
		787890 EPS15_HUMAN (1-788): 4.17e-139: 435: 88.34		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		787903 EPS15_HUMAN (1-788): 4.17e-139: 435: 88.34		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Rn
		923853 Q5JC29_RAT (1-792): 1.51e-137: 427: 100.00		AP2B1_RAT (36-934): 0: 629: 16.82
+	Hs
		212604 EPS15_HUMAN (1-788): 4.17e-139: 435: 88.34		AP1G1_HUMAN (1-824): 0: 599: 24.91
+	Mm
		788007 EPS15_MOUSE (1-777): 4.77e-126: 400: 94.34		AP2B1_MOUSE (36-934): 0: 628: 16.72
+	Hs
		302157 ITSN1_HUMAN (2-530): 3.39e-32: 137: 13.75		AP2A2_HUMAN (1-939): 0: 866: 95.85
+	Hs
		321552 ITSN1_HUMAN (2-530): 3.39e-32: 137: 13.75		AP2A1_HUMAN (1-939): 0: 833: 78.67
+	Ce
		1094946 Q9U2T9_CAEEL (6-767): 5.71e-42: 167: 14.23		Q22601_CAEEL (3-939): 0: 794: 64.44
+	Hs
		926038 EP15R_HUMAN (1-790): 2.69e-95: 318: 41.01		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		1014098 EP15R_HUMAN (1-790): 2.69e-95: 318: 41.01		AP1B1_HUMAN (36-934): 0: 625: 17.55
+	Rn
		923861 ITSN1_RAT (9-776): 1.45e-80: 285: 16.87		AP2B1_RAT (36-934): 0: 629: 16.82
+	Hs
		926031 ITSN2_HUMAN (6-783): 1.02e-70: 255: 15.39		AP2B1_HUMAN (36-934): 0: 629: 16.82
+	Hs
		1014096 ITSN2_HUMAN (6-783): 1.02e-70: 255: 15.39		AP1B1_HUMAN (36-934): 0: 625: 17.55