Protein: BECN1
Vacuolar protein sorting-associated protein 30 (Autophagy-related protein 6)

Gene: BECN1, VPS30
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: Q02948

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797190

ATG14
Autophagy-related protein 14

8

0

Small-scale

0.923

High

649848

VPS34
Phosphatidylinositol 3-kinase VPS34

8

8

Small-scale

0.751

High

646686

VPS15
Serine/threonine-protein kinase VPS15

5

4

Small-scale

0.709

High

1039913

VPS38
Vacuolar protein sorting-associated protein 38

6

0

Small-scale

0.708

High

722201

XPO1
Exportin-1

3

2

Small-scale

0.661

High

1039912

ATG38
PtdIns3K complex I subunit atg38

2

0

Small-scale

0.577

High

917153

ATG1
Serine/threonine-protein kinase ATG1

1

2

Small-scale

0.501

High

458603

SEC4
Ras-related protein SEC4

1

1

High-throughput

0.479

High

616446

SEC18
Vesicular-fusion protein SEC18

1

2

High-throughput

0.479

High

635044

VPS33
Vacuolar protein sorting-associated protein 33

1

1

High-throughput

0.479

High

656594

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.479

High

698119

PEP3
Vacuolar membrane protein PEP3

1

1

High-throughput

0.479

High

733819

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

1

High-throughput

0.479

High

745384

EMP24
Endosomal protein P24B

1

1

High-throughput

0.479

High

748773

YPT7
Ypt/Rab-type GTPase YPT7

1

1

High-throughput

0.479

High

758137

CASP
Protein CASP

1

3

High-throughput

0.479

High

779633

VPS21
Vacuolar protein sorting-associated protein 21

1

2

High-throughput

0.479

High

781334

DID4
DOA4-independent degradation protein 4

1

1

High-throughput

0.479

High

803095

GOSR1
Golgi SNAP receptor complex member 1

1

2

High-throughput

0.479

High

803791

NEL1
GTPase-activating protein NEL1

1

1

High-throughput

0.479

High

809128

AKR1
Palmitoyltransferase AKR1

1

1

High-throughput

0.479

High

813921

ERV46
ER-derived vesicles protein ERV46

1

1

High-throughput

0.479

High

815052

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.479

High

815873

KC13
Casein kinase I homolog 3

1

2

High-throughput

0.479

High

824617

VTH1
VPS10 homolog 1

1

1

High-throughput

0.479

High

923820

YIF1
Protein transport protein YIF1

1

1

High-throughput

0.479

High

932624

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.479

High

999491

DID2
Vacuolar protein-sorting-associated protein 46

1

1

High-throughput

0.479

High

1031142

SED5
Integral membrane protein SED5

1

1

High-throughput

0.479

High

1039908

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

1

High-throughput

0.479

High

1039910

ERV41
ER-derived vesicles protein ERV41

1

1

High-throughput

0.479

High

646513

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.460

High

376336

YPT1
GTP-binding protein YPT1

1

0

High-throughput

0.458

High

435310

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

556617

PEP5
E3 ubiquitin-protein ligase PEP5

1

0

High-throughput

0.458

High

564760

ATC1
Calcium-transporting ATPase 1

1

0

High-throughput

0.458

High

582510

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.458

High

633570

SAR1
Small COPII coat GTPase SAR1

1

0

High-throughput

0.458

High

639055

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.458

High

646199

SLY1
Protein SLY1

1

0

High-throughput

0.458

High

646263

SEC22
Protein transport protein SEC22

1

0

High-throughput

0.458

High

652938

BET1
Protein transport protein BET1

1

0

High-throughput

0.458

High

673646

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.458

High

674798

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.458

High

679998

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

732184

COPG
Coatomer subunit gamma

1

0

High-throughput

0.458

High

743476

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

746144

PEP12
Syntaxin PEP12

1

0

High-throughput

0.458

High

746459

SSO1
Protein SSO1

1

0

High-throughput

0.458

High

748271

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.458

High

782623

TVP38
Golgi apparatus membrane protein TVP38

1

0

High-throughput

0.458

High

790341

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.458

High

794794

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.458

High

800393

YPT31
GTP-binding protein YPT31/YPT8

1

0

High-throughput

0.458

High

806241

SVP26
Protein SVP26

1

0

High-throughput

0.458

High

815102

SS120
Protein SSP120

1

0

High-throughput

0.458

High

815999

VAC8
Vacuolar protein 8

1

0

High-throughput

0.458

High

825931

ATC7
Phospholipid-transporting ATPase NEO1

1

0

High-throughput

0.458

High

825975

GVP36
Protein GVP36

1

0

High-throughput

0.458

High

835084

SYS1
Protein SYS1

1

0

High-throughput

0.458

High

849656

EMP47
Protein EMP47

1

0

High-throughput

0.458

High

851254

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.458

High

916565

YIP1
Protein transport protein YIP1

1

0

High-throughput

0.458

High

918664

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

922199

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.458

High

1039909

VTI1
t-SNARE VTI1

1

0

High-throughput

0.458

High

1039914

YOP1
Protein YOP1

1

0

High-throughput

0.458

High

546011

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

819598

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

672449

STE50
Protein STE50

1

0

High-throughput

0.438

High

1039911

ERP1
Protein ERP1

1

2

High-throughput

0.437

High

403633

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

592454

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

885068

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

506472

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

739737

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

801099

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

917979

PRM8
Pheromone-regulated membrane protein 8

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025