HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: IASPP (Q8WUF5)
RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein)
Gene: PPP1R13L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2229 Hs			1 828
+	Hs
		1127642 PRC2B_HUMAN (1-2229): 0: 619: 100.00		ANKH1_HUMAN (483-715): 2.86e-22: 105: 16.24
+	Hs
		1127674 PRC2B_HUMAN (1-2229): 0: 619: 100.00		EHMT2_HUMAN (72-828): 2.83e-19: 95.5: 9.69
+	Hs
		862053 PRC2B_HUMAN (1-2229): 0: 619: 100.00		DAPK1_HUMAN (483-679): 2.8e-16: 85.9: 11.56
+	Mm
		1126575 SRRM2_MOUSE (35-1972): 1.31e-26: 122: 11.23		IASPP_MOUSE (1-825): 4.7e-107: 349: 88.12
+	Hs
		965154 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		Q9H4D1_HUMAN (258-794): 4.17e-56: 208: 11.81
+	Hs
		166913 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		ANR28_HUMAN (481-815): 8.93e-52: 198: 13.68
+	Mm
		103608 ANK2_MOUSE (294-2229): 1.18e-56: 221: 9.75		ANK3_MOUSE (413-712): 6.48e-31: 133: 12.58
+	Hs
		883487 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		RIPK4_HUMAN (471-722): 2.55e-35: 146: 17.26
+	Dm
		65570 FUTSC_DROME (353-2229): 1.74e-50: 201: 9.19		A8JNM5_DROME (416-712): 7.16e-29: 127: 13.04
+	Hs
		166985 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		ANR28_HUMAN (481-815): 8.93e-52: 198: 13.68
+	Hs
		862028 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		DAPK1_HUMAN (483-679): 2.8e-16: 85.9: 11.56
+	Hs
		1056981 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		TNKS2_HUMAN (535-828): 4.07e-52: 199: 14.13
+	Hs
		225134 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		MYPT2_HUMAN (640-746): 1.15e-10: 67.5: 27.52
+	Hs
		821082 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		ANR50_HUMAN (533-828): 3.38e-53: 203: 14.69
+	Hs
		310053 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		TNKS1_HUMAN (426-751): 4.58e-42: 168: 14.61
+	Hs
		556716 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		ANK1_HUMAN (416-712): 5.63e-32: 136: 13.04
+	Dm
		1182373 Q9VLS7_DROME (949-2220): 1.76e-09: 65.6: 9.45		Q7KU92_DROME (416-712): 1.65e-29: 129: 13.04
+	Hs
		1296398 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		EHMT2_HUMAN (72-828): 2.83e-19: 95.5: 9.69
+	Hs
		820969 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		ANKH1_HUMAN (483-715): 2.86e-22: 105: 16.24
+	Mm
		1351630 PCLO_MOUSE (15-1858): 1.65e-14: 82.4: 8.18		PCLO_MOUSE (41-630): 9.32e-12: 71.6: 14.05