HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2229 Hs			1 523
+	Hs
		516546 PRC2B_HUMAN (1-2229): 0: 619: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		965106 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		965152 ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29		PABP3_HUMAN (4-522): 2.67e-63: 219: 13.06
+	Hs
		1263596 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		1049608 EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516749 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		1069707 NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		1069826 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		516766 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613619 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		516609 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613628 PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1288650 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1069770 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		516406 PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613557 CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		613456 MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1031405 TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1020354 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1077540 SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11