Interactor 1: IQEC2 (Q5JU85)
IQ motif and SEC7 domain-containing protein 2
Gene: IQSEC2

Interactor 2: IQEC1 (Q6DN90)
IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)
Gene: IQSEC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IQ_SEC7_PH~Sec7, Sec7~Sec7
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0030036 - actin cytoskeleton organization
GO:0032012 - regulation of ARF protein signal transduction
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1488
Hs

1 963
+ Hs
+ Zm
+ Sp
+ Hs
+ Hs
+ Sc
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024