HitPredict

Interactor 1: Q5K373 (Q5K373)
FGF receptor-like protein 1b beta (Fibroblast growth factor receptor-like 1b) (Fibroblast growth factor receptor-like 1b precursor)
Gene: fgfrl1b

Interactor 2: FGFR2 (Q8JG38)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1)
Gene: FGFR2

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20802085
Identification Methods	solid phase assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~I-set, Ig_3~I-set
Common GO terms	GO:0005007 - fibroblast growth factor receptor activity GO:0005886 - plasma membrane GO:0017134 - fibroblast growth factor binding GO:0051216 - cartilage development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 481 Dr			1 817
+	Dr
		47576 Q7SX76_DANRE (22-481): 3.21e-100: 310: 55.65		A0A8M9Q9W6_DANRE (23-817): 0: 739: 64.54
+	Hs
		507980 PTPRS_HUMAN (20-452): 5.23e-73: 253: 20.61		FGFR1_HUMAN (1-816): 0: 759: 65.82
+	Hs
		507856 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		FGFR1_HUMAN (1-816): 0: 759: 65.82
+	Hs
		507854 FGFR2_HUMAN (141-475): 5.71e-32: 132: 14.80		FGFR1_HUMAN (1-816): 0: 759: 65.82
+	Hs
		1031989 PTPRS_HUMAN (20-452): 5.23e-73: 253: 20.61		NTRK3_HUMAN (112-768): 9.01e-175: 526: 23.07
+	Hs
		607974 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		EPHA7_HUMAN (7-791): 0: 609: 19.78
+	Hs
		607929 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		EPHA4_HUMAN (2-790): 0: 608: 20.05
+	Hs
		607887 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		EPHA2_HUMAN (7-796): 0: 576: 20.40
+	Hs
		384777 PTPRS_HUMAN (20-452): 5.23e-73: 253: 20.61		NTRK1_HUMAN (168-769): 3.17e-144: 446: 26.71
+	Rn
		976067 PTPRS_RAT (6-476): 1.15e-33: 137: 15.13		NTRK3_RAT (132-768): 7.8e-171: 517: 24.15
+	Hs
		434136 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		RET_HUMAN (409-784): 1.46e-95: 324: 45.31
+	Dr
		60114 Q5K373_DANRE (1-481): 4.01e-124: 372: 100.00		A4QN31_DANRE (1-263): 2.11e-18: 92.1: 26.54
+	Dr
		1128952 Q5K373_DANRE (1-481): 4.01e-124: 372: 100.00		FGFR4_DANRE (43-387): 3.76e-11: 68.9: 18.56
+	Dr
		60115 Q7SX76_DANRE (22-481): 3.21e-100: 310: 55.65		A4QN31_DANRE (1-263): 2.11e-18: 92.1: 26.54
+	Dr
		1186346 Q7SX76_DANRE (22-481): 3.21e-100: 310: 55.65		FGFR4_DANRE (43-387): 3.76e-11: 68.9: 18.56
+	Hs
		608212 ROBO1_HUMAN (109-480): 2.82e-42: 163: 16.71		FGFR4_HUMAN (5-254): 5.91e-19: 94: 14.93
+	Hs
		607878 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		FGFR4_HUMAN (5-254): 5.91e-19: 94: 14.93
+	Hs
		607959 FGFR4_HUMAN (131-479): 8.27e-36: 143: 15.45		PTK7_HUMAN (171-360): 8.79e-15: 80.9: 15.54
+	Dr
		65451 A8DZ85_DANRE (151-480): 5.62e-38: 150: 16.91		VGFR4_DANRE (33-378): 9.31e-11: 67.8: 16.11
+	Dr
		1206297 FGR1A_DANRE (143-475): 1.48e-34: 139: 13.45		VGFR4_DANRE (33-378): 9.31e-11: 67.8: 16.11