Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: BORG2 (Q9UKI2)
Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein)
Gene: CDC42EP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 29513927, 24947832
Identification Methods pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2527
Hs

1 254
+ Hs
+ Hs

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Last updated: 15 Jul 2024