HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.-) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	28977666, 32744500, 21555454
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 699
+	Hs
		1039499 CHD4_HUMAN (1-1912): 0: 1708: 100.00		TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16
+	Hs
		542516 CHD4_HUMAN (1-1912): 0: 1708: 100.00		TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44
+	Hs
		1088349 CHD3_HUMAN (20-1905): 0: 1570: 66.98		NOLC1_HUMAN (1-699): 1.83e-63: 226: 100.00
+	Hs
		1039487 CHD3_HUMAN (20-1905): 0: 1570: 66.98		TOP2B_HUMAN (6-463): 6.99e-58: 215: 14.16
+	Hs
		1132862 CHD4_HUMAN (1-1912): 0: 1708: 100.00		TITIN_HUMAN (19-560): 1.43e-11: 70.4: 12.03
+	Hs
		1132895 CHD4_HUMAN (1-1912): 0: 1708: 100.00		CHAP1_HUMAN (7-377): 7.52e-11: 67.8: 11.59
+	Hs
		542487 CHD3_HUMAN (20-1905): 0: 1570: 66.98		TOP2A_HUMAN (6-372): 2.3e-38: 155: 14.44
+	Dm
		356890 CHDM_DROME (86-1904): 0: 1370: 52.89		Q9VPR2_DROME (26-491): 1.52e-19: 95.5: 12.58