HitPredict

Interactor 1: WLS (Q5T9L3)
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
Gene: WLS

Interactor 2: WNT16 (Q9UBV4)
Protein Wnt-16
Gene: WNT16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MIG-14_Wnt-bd~wnt
Common GO terms	GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 365
+	Mm
		568285 WLS_MOUSE (1-541): 0: 812: 96.12		WNT3_MOUSE (31-365): 7.02e-145: 416: 41.28
+	Hs
		881881 WLS_HUMAN (1-541): 0: 811: 100.00		WNT4_HUMAN (11-365): 2.12e-144: 414: 41.39
+	Mm
		611175 WLS_MOUSE (1-541): 0: 812: 96.12		WNT5A_MOUSE (17-365): 1.37e-141: 408: 38.74
+	Hs
		782089 WLS_HUMAN (1-541): 0: 811: 100.00		WNT5A_HUMAN (7-365): 5.19e-142: 409: 38.10
+	Hs
		1135438 WLS_HUMAN (1-541): 0: 811: 100.00		WNT5B_HUMAN (28-365): 1.06e-141: 407: 41.67
+	Hs
		451998 WLS_HUMAN (1-541): 0: 811: 100.00		WNT2_HUMAN (30-365): 1.57e-139: 402: 40.83
+	Hs
		881860 WLS_HUMAN (1-541): 0: 811: 100.00		WNT3A_HUMAN (31-365): 1.5e-139: 402: 40.70
+	Hs
		881899 WLS_HUMAN (1-541): 0: 811: 100.00		WNT7B_HUMAN (21-365): 9.33e-138: 397: 43.88
+	Hs
		135861 WLS_HUMAN (1-541): 0: 811: 100.00		WNT7A_HUMAN (32-365): 3.38e-137: 395: 42.44
+	Mm
		382254 WLS_MOUSE (1-541): 0: 812: 96.12		WNT1_MOUSE (33-364): 2.13e-129: 377: 37.32
+	Hs
		384072 WLS_HUMAN (1-541): 0: 811: 100.00		WNT1_HUMAN (33-364): 1.62e-129: 377: 37.32
+	Hs
		158076 WLS_HUMAN (1-541): 0: 811: 100.00		WNT9B_HUMAN (35-365): 1.9e-113: 335: 37.50
+	Hs
		1135437 WLS_HUMAN (1-541): 0: 811: 100.00		WNT8A_HUMAN (69-364): 2.79e-112: 332: 36.45
+	Hs
		158068 WLS_HUMAN (1-541): 0: 811: 100.00		WNT9A_HUMAN (46-365): 1.14e-110: 329: 33.23
+	Hs
		1135420 WLS_HUMAN (1-541): 0: 811: 100.00		WNT8B_HUMAN (68-364): 4.12e-104: 312: 37.46
+	Dm
		658764 WLS_DROME (1-535): 0: 642: 40.82		WNT2_DROME (47-365): 2.07e-113: 335: 37.50
+	Dm
		776060 WLS_DROME (1-535): 0: 642: 40.82		WNT4_DROME (45-365): 1.22e-101: 312: 33.13
+	Dm
		658776 WLS_DROME (1-535): 0: 642: 40.82		WNT5_DROME (48-207): 1.86e-44: 165: 29.81
+	Dm
		452324 WLS_DROME (1-535): 0: 642: 40.82		WNTG_DROME (262-364): 5.14e-37: 140: 41.75
+	Dm
		1279554 WLS_DROME (1-535): 0: 642: 40.82		Q9VM25_DROME (260-364): 1.02e-25: 109: 38.10