HitPredict

Interactor 1: CND2 (Q15003)
Condensin complex subunit 2 (Barren homolog protein 1) (Chromosome-associated protein H) (hCAP-H) (Non-SMC condensin I complex subunit H) (XCAP-H homolog)
Gene: NCAPH

Interactor 2: SMC4 (Q9NTJ3)
Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog)
Gene: SMC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.947

The method score is based on:

Property	Details
Experiments	26496610, 26166704, 24981860, 35271311, 39358380, 17268547
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Cnd2~SMC_N
Common GO terms	GO:0000794 - condensed nuclear chromosome GO:0000796 - condensin complex GO:0003682 - chromatin binding GO:0005654 - nucleoplasm GO:0005829 - cytosol and 6 others more... GO:0007076 - mitotic chromosome condensation GO:0010032 - meiotic chromosome condensation GO:0051301 - cell division GO:0051984 - positive regulation of chromosome segregation GO:1905820 - positive regulation of chromosome separation GO:1905821 - positive regulation of chromosome condensation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	741
Hs

1	1288

Service provided by Combinatics, Japan

Last updated: 11Aug2025