HitPredict

Interactor 1: G5EG22 (G5EG22)
Methylosome subunit pICln
Gene: icln-1

Interactor 2: SMD3 (Q17348)
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)
Gene: snr-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	1.00	0.637

Property	Details
Experiments	19123269
Identification Methods	two hybrid array, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LSM~Voldacs
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 225 Ce			1 136
+	Ce
		113616 G5EFZ5_CAEEL (1-225): 1.45e-70: 215: 90.67		SMD3_CAEEL (1-136): 8.51e-49: 154: 100.00
+	Ce
		113637 G5EG22_CAEEL (1-225): 7.33e-77: 232: 100.00		SMD1_CAEEL (8-92): 1.48e-29: 105: 27.06
+	Ce
		113615 G5EFZ5_CAEEL (1-225): 1.45e-70: 215: 90.67		SMD1_CAEEL (8-92): 1.48e-29: 105: 27.06
+	Hs
		926252 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		LSM4_HUMAN (6-91): 6.17e-35: 119: 27.59
+	Hs
		926165 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		SMD3_HUMAN (3-115): 8.38e-34: 116: 59.29
+	Hs
		926163 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		SMD1_HUMAN (8-100): 1.55e-32: 112: 25.81
+	Hs
		926249 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		LSM2_HUMAN (9-96): 2.5e-32: 111: 22.22
+	Hs
		926214 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		LSM10_HUMAN (8-118): 1.59e-31: 110: 22.52
+	Dm
		57265 ICLN_DROME (1-212): 8.2e-54: 173: 16.81		Q9VTW6_DROME (9-92): 2.7e-32: 111: 24.42
+	Hs
		926159 ICLN_HUMAN (2-213): 9.56e-56: 179: 28.70		RUXF_HUMAN (7-73): 1.71e-27: 98.9: 29.85
+	Dm
		57256 ICLN_DROME (1-212): 8.2e-54: 173: 16.81		RUXF_DROME (3-73): 5.35e-22: 85.1: 29.73
+	Sp
		151307 ICLN_SCHPO (33-192): 1.6e-35: 126: 23.60		SMD1_SCHPO (8-97): 1.09e-31: 110: 23.33
+	Sp
		151317 ICLN_SCHPO (33-192): 1.6e-35: 126: 23.60		SMD3_SCHPO (4-101): 1.87e-31: 109: 53.06