HitPredict

Interactor 1: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Interactor 2: CLIP4 (Q8N3C7)
CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)
Gene: CLIP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2346 Hs			1 705
+	Hs
		1232235 CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90		CLIP4_HUMAN (1-705): 0: 943: 100.00
+	Hs
		1138322 MYOME_HUMAN (1-2346): 0: 703: 100.00		CYLD_HUMAN (267-590): 4.08e-58: 214: 14.75
+	Hs
		675182 MYOME_HUMAN (1-2346): 0: 703: 100.00		CLIP1_HUMAN (596-699): 8.45e-25: 112: 30.77
+	Mm
		93502 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		E9Q4K7_MOUSE (556-692): 1.04e-25: 116: 30.87
+	Mm
		1194568 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		CLIP2_MOUSE (547-702): 1.57e-25: 114: 22.93
+	Mm
		1194545 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		CLIP1_MOUSE (584-699): 2.63e-24: 111: 30.77
+	Hs
		969585 CENPE_HUMAN (1-1839): 1.04e-60: 234: 11.33		DCTN1_HUMAN (598-701): 1.84e-30: 130: 36.54
+	Hs
		1137846 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		CE350_HUMAN (547-704): 2.31e-28: 124: 22.56
+	Hs
		675226 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		CLIP1_HUMAN (596-699): 8.45e-25: 112: 30.77
+	Hs
		725251 MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20		CYLD_HUMAN (267-590): 4.08e-58: 214: 14.75
+	Hs
		725032 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		CYLD_HUMAN (267-590): 4.08e-58: 214: 14.75
+	Hs
		166706 CE290_HUMAN (10-915): 3.83e-20: 100: 9.92		DCTN1_HUMAN (598-701): 1.84e-30: 130: 36.54
+	Hs
		166725 CE290_HUMAN (10-915): 3.83e-20: 100: 9.92		CE350_HUMAN (547-704): 2.31e-28: 124: 22.56
+	Hs
		1051424 CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90		DCTN1_HUMAN (598-701): 1.84e-30: 130: 36.54
+	Hs
		1137843 CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90		CE350_HUMAN (547-704): 2.31e-28: 124: 22.56
+	Mm
		139891 CE290_MOUSE (1-666): 3.82e-13: 77.7: 10.25		DCTN1_MOUSE (598-701): 7.52e-31: 131: 35.58
+	Mm
		1112041 CE290_MOUSE (1-666): 3.82e-13: 77.7: 10.25		Q3TRF1_MOUSE (598-701): 1.48e-30: 126: 35.58
+	Hs
		725033 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		KI13B_HUMAN (551-692): 3.95e-26: 117: 29.45
+	Dm
		528056 LVA_DROME (1-683): 7.78e-12: 73.5: 11.35		DCTN1_DROME (621-693): 1.64e-24: 111: 43.84
+	Dm
		1229141 LVA_DROME (1-683): 7.78e-12: 73.5: 11.35		CL190_DROME (547-700): 6.87e-23: 106: 22.73