HitPredict

Interactor 1: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Interactor 2: MIB1 (Q86YT6)
E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)
Gene: MIB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 321 Hs			1 1006
+	Hs
		1206094 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		MIB1_HUMAN (1-1006): 0: 867: 100.00
+	Hs
		849363 UB2D1_HUMAN (4-153): 1.02e-75: 230: 30.00		MIB1_HUMAN (1-1006): 0: 867: 100.00
+	Hs
		919776 UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67		MIB1_HUMAN (1-1006): 0: 867: 100.00
+	Hs
		895841 UB2D3_HUMAN (4-153): 1.55e-74: 227: 34.00		MIB1_HUMAN (1-1006): 0: 867: 100.00
+	Hs
		1138900 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		MIB2_HUMAN (14-1006): 0: 593: 29.05
+	Hs
		849396 UB2D1_HUMAN (4-153): 1.02e-75: 230: 30.00		MIB2_HUMAN (14-1006): 0: 593: 29.05
+	Hs
		919813 UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67		MIB2_HUMAN (14-1006): 0: 593: 29.05
+	Hs
		829062 UBE2A_HUMAN (1-151): 5.75e-68: 210: 33.11		Q9H4D1_HUMAN (397-718): 4.03e-26: 117: 31.00