Protein: PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1)

Gene: PDP1
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9P0J1

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004741 - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0019909 - [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1344951

LATS2
Serine/threonine-protein kinase LATS2

1

6

High-throughput

0.691

High

1026238

PAK1
Serine/threonine-protein kinase PAK 1

2

16

High-throughput

0.659

High

1317865

RM37
Large ribosomal subunit protein mL37

3

0

High-throughput

0.638

High

440779

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

3

0

Small-scale

0.632

High

678097

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

2

1

High-throughput

0.628

High

984545

KPCD
Protein kinase C delta type

1

4

Small-scale

0.618

High

718436

PCGF2
Polycomb group RING finger protein 2

2

0

High-throughput

0.602

High

1241813

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

2

0

High-throughput

0.602

High

228935

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

624005

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

1

Small-scale

0.578

High

1345679

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

4

Small-scale

0.578

High

1347977

TRM1
tRNA

2

0

High-throughput

0.576

High

297137

PKHG5
Pleckstrin homology domain-containing family G member 5

2

1

High-throughput

0.574

High

520182

BMP4
Bone morphogenetic protein 4

2

1

High-throughput

0.574

High

1129607

SMAG2
Protein Smaug homolog 2

2

1

High-throughput

0.574

High

1191415

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

2

1

High-throughput

0.574

High

203470

MTG8R
Protein CBFA2T2

1

0

High-throughput

0.549

High

265069

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.536

High

506071

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

526462

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.536

High

1014534

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.536

High

900991

RHOA
Transforming protein RhoA

2

2

High-throughput

0.521

High

829345

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1035360

TOP3A
DNA topoisomerase 3-alpha

1

0

High-throughput

0.513

High

1064977

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1087740

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.513

High

1241432

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.513

High

159410

PLD2
Phospholipase D2

1

2

High-throughput

0.489

High

362598

C1QC
Complement C1q subcomponent subunit C

1

1

High-throughput

0.489

High

963442

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

2

High-throughput

0.489

High

1045550

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

2

High-throughput

0.489

High

1050630

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

3

High-throughput

0.489

High

1079703

ADIPO
Adiponectin

1

1

High-throughput

0.489

High

1127504

WDR44
WD repeat-containing protein 44

1

1

High-throughput

0.489

High

1301660

RB40C
Ras-related protein Rab-40C

1

8

High-throughput

0.489

High

1329159

IL25
Interleukin-25

1

1

High-throughput

0.489

High

1349582

SMAG1
Protein Smaug homolog 1

1

1

High-throughput

0.489

High

377752

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

1068108

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

1349583

PKP3
Plakophilin-3

1

1

High-throughput

0.470

High

1151277

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

263010

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

1128281

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

175266

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.457

High

339061

EGFR
Epidermal growth factor receptor

1

14

Small-scale

0.457

High

508235

FGFR1
Fibroblast growth factor receptor 1

1

10

Small-scale

0.457

High

1349584

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

4

High-throughput

0.445

High

838324

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1344781

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

504880

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.437

High

951417

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.437

High

1172050

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

305089

SPN1
Snurportin-1

3

0

High-throughput

0.347

High

1012370

INCA1
Protein INCA1

2

0

High-throughput

0.316

High

1109274

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

657687

LYOX
Protein-lysine 6-oxidase

1

0

High-throughput

0.279

Low

1037564

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

0

High-throughput

0.279

Low

1166398

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

1192077

AP2D
Transcription factor AP-2-delta

1

0

High-throughput

0.279

Low

1235295

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

1345398

CHST7
Carbohydrate sulfotransferase 7

1

0

High-throughput

0.279

Low

1348520

DLL3
Delta-like protein 3

1

0

High-throughput

0.279

Low

1349581

COR1C
Coronin-1C

1

0

High-throughput

0.279

Low

60524

CL18A
C-type lectin domain family 18 member A

1

0

High-throughput

0.249

Low

1085701

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024