HitPredict

Interactor 1: BROX (Q5VW32)
BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)
Gene: BROX

Interactor 2: CHM4A (Q9BY43)
Charged multivesicular body protein 4a (Chromatin-modifying protein 4a) (CHMP4a) (SNF7 homolog associated with Alix-2) (SNF7-1) (hSnf-1) (Vacuolar protein sorting-associated protein 32-1) (Vps32-1) (hVps32-1)
Gene: CHMP4A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	22484091
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 411 Hs			1 222
+	Hs
		1138944 BROX_HUMAN (1-411): 0: 517: 100.00		CHM4C_HUMAN (1-222): 1.11e-45: 153: 52.56
+	Hs
		1138947 BROX_HUMAN (1-411): 0: 517: 100.00		CHM4B_HUMAN (1-221): 3.37e-45: 151: 61.61
+	Hs
		1138950 BROX_HUMAN (1-411): 0: 517: 100.00		CHMP5_HUMAN (4-220): 5.25e-44: 148: 26.91
+	Hs
		1330347 PTN23_HUMAN (42-397): 4.86e-93: 307: 19.01		CHM4B_HUMAN (1-221): 3.37e-45: 151: 61.61
+	Hs
		1260391 PDC6I_HUMAN (39-392): 2.3e-82: 271: 18.89		CHM4A_HUMAN (1-222): 5.74e-48: 158: 100.00
+	Dm
		1249821 Q9VUH6_DROME (30-392): 5.75e-79: 267: 20.11		CHM4_DROME (1-222): 2.66e-47: 157: 51.95
+	Hs
		1260376 PDC6I_HUMAN (39-392): 2.3e-82: 271: 18.89		CHM4C_HUMAN (1-222): 1.11e-45: 153: 52.56
+	Hs
		1260401 PDC6I_HUMAN (39-392): 2.3e-82: 271: 18.89		CHM4B_HUMAN (1-221): 3.37e-45: 151: 61.61
+	Dm
		1249814 Q9VB05_DROME (34-406): 6.29e-77: 256: 18.64		CHM4_DROME (1-222): 2.66e-47: 157: 51.95
+	Sc
		764903 PALA_YEAST (9-391): 2.88e-72: 240: 17.14		SNF7_YEAST (3-208): 8.55e-32: 117: 37.50
+	At
		95250 BRO1_ARATH (29-387): 2.91e-66: 227: 18.56		VP322_ARATH (3-221): 2.19e-36: 129: 34.69
+	Sc
		764862 BRO1_YEAST (39-398): 2.62e-69: 235: 20.32		SNF7_YEAST (3-208): 8.55e-32: 117: 37.50
+	Sc
		820024 BRO1_YEAST (39-398): 2.62e-69: 235: 20.32		VPS20_YEAST (10-212): 4.65e-30: 112: 22.01
+	At
		95242 BRO1_ARATH (29-387): 2.91e-66: 227: 18.56		VP321_ARATH (3-221): 9.68e-33: 119: 35.00