Protein: R3HD2
R3H domain-containing protein 2

Gene: R3HD2, R3HDM2
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q9Y2K5

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

730379

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.697

High

967048

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

1138959

R3HD1
R3H domain-containing protein 1

1

9

High-throughput

0.618

High

950730

KR108
Keratin-associated protein 10-8

3

5

High-throughput

0.616

High

1049931

1433F
14-3-3 protein eta

3

20

High-throughput

0.604

High

691562

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

1366634

AKAP1
A-kinase anchor protein 1, mitochondrial

2

1

High-throughput

0.584

High

1081518

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1277450

NT2NA
Notch homolog 2 N-terminal-like protein A

2

5

High-throughput

0.578

High

1369879

CELF1
CUGBP Elav-like family member 1

2

7

High-throughput

0.576

High

1049065

REL
Proto-oncogene c-Rel

1

13

High-throughput

0.573

High

221434

SPY3
Protein sprouty homolog 3

2

2

High-throughput

0.553

High

300533

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.553

High

950440

KR107
Keratin-associated protein 10-7

2

8

High-throughput

0.553

High

1059764

KRA11
Keratin-associated protein 1-1

2

5

High-throughput

0.553

High

1146221

K1H1
Keratin, type I cuticular Ha1

2

1

High-throughput

0.553

High

1250337

ATL4
ADAMTS-like protein 4

2

1

High-throughput

0.553

High

1307476

KRA13
Keratin-associated protein 1-3

2

5

High-throughput

0.553

High

1311487

TRI42
Tripartite motif-containing protein 42

2

20

High-throughput

0.553

High

1410120

KR412
Keratin-associated protein 4-12

2

7

High-throughput

0.553

High

1372125

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.549

High

972161

1433E
14-3-3 protein epsilon

1

7

High-throughput

0.536

High

990896

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

221403

SPY1
Protein sprouty homolog 1

1

2

High-throughput

0.523

High

927620

ATX1
Ataxin-1

1

5

High-throughput

0.508

High

48110

RBM47
RNA-binding protein 47

1

6

High-throughput

0.479

High

50427

MEX3A
RNA-binding protein MEX3A

1

10

High-throughput

0.479

High

64160

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.479

High

124982

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.479

High

143341

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

164667

TNPO2
Transportin-2

1

2

High-throughput

0.479

High

183535

CASC3
Protein CASC3

1

8

High-throughput

0.479

High

273956

CNOT3
CCR4-NOT transcription complex subunit 3

1

8

High-throughput

0.479

High

341708

EYA4
Protein phosphatase EYA4

1

16

High-throughput

0.479

High

352603

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

550533

PABP1
Polyadenylate-binding protein 1

1

4

High-throughput

0.479

High

623599

RO52
E3 ubiquitin-protein ligase TRIM21

1

4

High-throughput

0.479

High

684441

DDX6
Probable ATP-dependent RNA helicase DDX6

1

5

High-throughput

0.479

High

688343

TTP
mRNA decay activator protein ZFP36

1

5

High-throughput

0.479

High

713877

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

7

High-throughput

0.479

High

838399

STA5A
Signal transducer and activator of transcription 5A

1

5

High-throughput

0.479

High

875841

PRC2A
Protein PRRC2A

1

20

High-throughput

0.479

High

1032446

OTUD4
OTU domain-containing protein 4

1

4

High-throughput

0.479

High

1122204

UBP2L
Ubiquitin-associated protein 2-like

1

17

High-throughput

0.479

High

1129541

PUM1
Pumilio homolog 1

1

4

High-throughput

0.479

High

1133748

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1148831

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

7

High-throughput

0.479

High

1165531

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

10

High-throughput

0.479

High

1206583

PRC2B
Protein PRRC2B

1

19

High-throughput

0.479

High

1213561

UBAP2
Ubiquitin-associated protein 2

1

16

High-throughput

0.479

High

1215432

TUT4
Terminal uridylyltransferase 4

1

2

High-throughput

0.479

High

1215905

RC3H1
Roquin-1

1

4

High-throughput

0.479

High

1252421

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1280780

YTHD3
YTH domain-containing family protein 3

1

12

High-throughput

0.479

High

1294596

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

4

High-throughput

0.479

High

1310680

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

1316491

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

1336893

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

20

High-throughput

0.479

High

1348145

PUM2
Pumilio homolog 2

1

5

High-throughput

0.479

High

1363363

DDX1
ATP-dependent RNA helicase DDX1

1

4

High-throughput

0.479

High

1364022

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

5

High-throughput

0.479

High

1365401

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

1370175

RENT1
Regulator of nonsense transcripts 1

1

3

High-throughput

0.479

High

1370262

DAZL
Deleted in azoospermia-like

1

12

High-throughput

0.479

High

1372171

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

2

High-throughput

0.479

High

1393984

FUBP3
Far upstream element-binding protein 3

1

7

High-throughput

0.479

High

1403252

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

2

High-throughput

0.479

High

1406527

ATX2
Ataxin-2

1

10

High-throughput

0.479

High

1412108

TRI56
E3 ubiquitin-protein ligase TRIM56

1

14

High-throughput

0.479

High

1419556

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

8

High-throughput

0.479

High

1429255

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

3

High-throughput

0.479

High

1434868

BICC1
Protein bicaudal C homolog 1

1

10

High-throughput

0.479

High

1435714

TDRD3
Tudor domain-containing protein 3

1

3

High-throughput

0.479

High

1437085

AGO3
Protein argonaute-3

1

6

High-throughput

0.479

High

1438090

RC3H2
Roquin-2

1

17

High-throughput

0.479

High

1438904

MOV10
Helicase MOV-10

1

3

High-throughput

0.479

High

1439118

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

18

High-throughput

0.479

High

1448129

4ET
Eukaryotic translation initiation factor 4E transporter

1

2

High-throughput

0.479

High

1451649

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.479

High

1453132

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

2

High-throughput

0.479

High

1453322

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

6

High-throughput

0.479

High

1453516

CNOT2
CCR4-NOT transcription complex subunit 2

1

7

High-throughput

0.479

High

1460495

CNOT7
CCR4-NOT transcription complex subunit 7

1

2

High-throughput

0.479

High

1461285

AGO2
Protein argonaute-2

1

6

High-throughput

0.479

High

1461382

AGO1
Protein argonaute-1

1

6

High-throughput

0.479

High

1462236

G3BP2
Ras GTPase-activating protein-binding protein 2

1

5

High-throughput

0.479

High

1462541

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

12

High-throughput

0.479

High

1462553

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

5

High-throughput

0.479

High

1490800

PRC2C
Protein PRRC2C

1

19

High-throughput

0.479

High

1490801

YTHD2
YTH domain-containing family protein 2

1

14

High-throughput

0.479

High

1490802

MAGD1
Melanoma-associated antigen D1

1

1

High-throughput

0.479

High

1490803

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

9

High-throughput

0.479

High

517140

NT2NC
Notch homolog 2 N-terminal-like protein C

1

6

High-throughput

0.470

High

1187097

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

1201708

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

High-throughput

0.458

High

1240522

DHX57
Putative ATP-dependent RNA helicase DHX57

1

0

High-throughput

0.458

High

1287231

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.458

High

1335336

FA98A
Protein FAM98A

1

0

High-throughput

0.458

High

1414716

MCRI2
MAPK regulated corepressor interacting protein 2

1

0

High-throughput

0.458

High

1490799

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

660

NBPFJ
NBPF family member NBPF19

1

6

High-throughput

0.439

High

950037

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

175272

SC16A
Protein transport protein Sec16A

1

12

High-throughput

0.437

High

176580

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.437

High

336146

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

6

High-throughput

0.437

High

338566

SC24B
Protein transport protein Sec24B

1

6

High-throughput

0.437

High

984339

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

6

High-throughput

0.437

High

1199407

GLE1
mRNA export factor GLE1

1

4

High-throughput

0.437

High

1241615

CEP85
Centrosomal protein of 85 kDa

1

6

High-throughput

0.437

High

1258219

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

1

High-throughput

0.437

High

1289211

N4BP2
NEDD4-binding protein 2

1

1

High-throughput

0.437

High

1356346

SMAP2
Stromal membrane-associated protein 2

1

4

High-throughput

0.437

High

1357615

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.437

High

1367828

TFG
Protein TFG

1

9

High-throughput

0.437

High

1411391

LZTS2
Leucine zipper putative tumor suppressor 2

1

6

High-throughput

0.437

High

1445969

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

9

High-throughput

0.437

High

70538

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

71536

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

949636

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

1187764

KR133
Keratin-associated protein 13-3

2

0

High-throughput

0.316

High

1241253

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

1364846

F168A
Protein FAM168A

1

0

High-throughput

0.299

High

1419128

KRA32
Keratin-associated protein 3-2

1

0

High-throughput

0.299

High

1191412

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

67513

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.249

Low

1420809

ZCHC2
Zinc finger CCHC domain-containing protein 2

1

0

High-throughput

0.249

Low

1439187

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.249

Low

1451604

TM160
Transmembrane protein 160

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025