HitPredict

Interactor 1: Q5XGX4 (Q5XGX4)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: rnf185.L

Interactor 2: Q7SY79 (Q7SY79)
Polyubiquitin-C (Ubc-prov protein)
Gene: ubc.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17558393
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Xl			1 609
+	Hs
		476198 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		476274 RNF5_HUMAN (12-154): 3.51e-42: 141: 62.94		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		475759 HLTF_HUMAN (2-158): 3.35e-29: 115: 18.47		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		475680 TRI26_HUMAN (22-111): 3.53e-26: 106: 30.77		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		476078 COP1_HUMAN (26-174): 5.05e-25: 102: 19.33		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		476418 TRI39_HUMAN (28-107): 7.62e-25: 102: 27.50		UBC_HUMAN (1-609): 0: 744: 99.84
+	Xl
		1186351 NF7B_XENLA (6-85): 4.82e-22: 94.4: 26.25		Q7SY79_XENLA (1-609): 0: 745: 100.00
+	Hs
		475753 TRI25_HUMAN (26-123): 3.29e-22: 94.9: 21.21		UBC_HUMAN (1-609): 0: 744: 99.84
+	Hs
		476188 RN125_HUMAN (1-86): 1e-20: 87.6: 26.74		UBC_HUMAN (1-609): 0: 744: 99.84
+	Mm
		476948 RN185_MOUSE (1-189): 1.13e-60: 188: 91.67		UBC_MOUSE (1-488): 0: 580: 97.95
+	Dm
		1215068 Q8IR26_DROME (14-188): 7.47e-53: 171: 52.27		Q9W418_DROME (153-609): 0: 558: 99.78
+	Dm
		1375478 Q9VXP1_DROME (14-189): 1.18e-59: 189: 57.39		R9PY16_DROME (381-609): 2.02e-84: 267: 90.39
+	Dm
		1215070 Q8IR26_DROME (14-188): 7.47e-53: 171: 52.27		R9PY16_DROME (381-609): 2.02e-84: 267: 90.39
+	Xl
		1140130 Q5XGX4_XENLA (1-189): 1.24e-64: 198: 100.00		Q6GMC1_XENLA (533-608): 3.78e-41: 148: 100.00
+	Hs
		924117 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		RS27A_HUMAN (533-608): 3.78e-41: 148: 100.00
+	Hs
		475137 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		UBB_HUMAN (1-77): 5.22e-26: 108: 98.70
+	Hs
		923989 TRI25_HUMAN (26-123): 3.29e-22: 94.9: 21.21		RS27A_HUMAN (533-608): 3.78e-41: 148: 100.00
+	Hs
		475134 TRI11_HUMAN (22-127): 1.15e-25: 104: 24.53		UBB_HUMAN (1-77): 5.22e-26: 108: 98.70
+	Sc
		477459 IRC20_YEAST (23-151): 9.08e-26: 105: 24.03		UBI4P_YEAST (1-77): 3.26e-23: 104: 94.81
+	Hs
		397963 TRI25_HUMAN (26-123): 3.29e-22: 94.9: 21.21		ISG15_HUMAN (228-380): 6.49e-21: 92: 32.69