HitPredict

Interactor 1: ITF2 (Q60722)
Transcription factor 4 (TCF-4) (Class A helix-loop-helix transcription factor ME2) (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: Tcf4

Interactor 2: Q6XZL8 (Q6XZL8)
Histone-lysine N-methyltransferase, H3 lysine-79 specific
Gene: Dot1l

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	22566624, 21103407
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 670 Mm			1 1540
+	Hs
		551217 ITF2_HUMAN (1-670): 0: 891: 97.32		DOT1L_HUMAN (1-1540): 0: 685: 82.76