Interactor 1: CRFR2 (Q60748)
Corticotropin-releasing factor receptor 2 (CRF-R-2) (CRF-R2) (CRFR-2) (CRF-RB) (Corticotropin-releasing hormone receptor 2) (CRH-R-2) (CRH-R2)
Gene: Crhr2

Interactor 2: UCN2 (Q99ML8)
Urocortin-2 (Urocortin II) (Ucn II)
Gene: UCN2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11416224
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~CRF, CRF~HRM
Common GO terms GO:0005179 - hormone activity
GO:0010629 - negative regulation of gene expression
GO:0033685 - negative regulation of luteinizing hormone secretion
GO:0046882 - negative regulation of follicle-stimulating hormone secretion
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 411
Mm

1 113
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024