Protein: PTN14
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)

Gene: PTN14, PTPN14
Organism: Homo sapiens
Interactions: 167
UniProt ID: Q15678

Gene Ontology (top 5):
GO:0001946 - lymphangiogenesis
GO:0003712 - transcription coregulator activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

808641

YAP1
Transcriptional coactivator YAP1

13

20

Small-scale

0.762

High

350191

RASK
GTPase KRas

2

20

High-throughput

0.754

High

915698

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1076894

KIBRA
Protein KIBRA

8

20

Small-scale

0.746

High

683372

1433B
14-3-3 protein beta/alpha

6

20

Small-scale

0.734

High

904597

1433G
14-3-3 protein gamma

5

20

High-throughput

0.718

High

982041

1433F
14-3-3 protein eta

5

20

High-throughput

0.712

High

1076929

PDLI7
PDZ and LIM domain protein 7

4

20

High-throughput

0.699

High

1076870

AMOT
Angiomotin

4

20

Small-scale

0.677

High

346877

MYC
Myc proto-oncogene protein

3

7

High-throughput

0.667

High

1076909

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

3

20

High-throughput

0.667

High

1076915

PAR6B
Partitioning defective 6 homolog beta

3

13

High-throughput

0.667

High

909595

1433E
14-3-3 protein epsilon

3

6

Small-scale

0.662

High

125485

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

10

Small-scale

0.640

High

325744

LATS1
Serine/threonine-protein kinase LATS1

3

11

Small-scale

0.640

High

1076877

WWC2
Protein WWC2

3

20

Small-scale

0.640

High

1076918

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

3

10

Small-scale

0.640

High

1076885

STXB4
Syntaxin-binding protein 4

4

18

High-throughput

0.633

High

1076872

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

2

20

High-throughput

0.628

High

1076914

PHF20
PHD finger protein 20

2

3

High-throughput

0.628

High

927076

1433Z
14-3-3 protein zeta/delta

2

20

Small-scale

0.621

High

146678

SOCS7
Suppressor of cytokine signaling 7

1

15

Small-scale

0.618

High

433778

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

547070

EZRI
Ezrin

1

18

High-throughput

0.618

High

876394

AFAD
Afadin

1

20

High-throughput

0.618

High

890681

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

5

Small-scale

0.618

High

894040

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

900503

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

925302

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1076866

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

18

High-throughput

0.618

High

1076893

KSR1
Kinase suppressor of Ras 1

1

20

High-throughput

0.618

High

1076886

ACD11
Acyl-CoA dehydrogenase family member 11

2

2

High-throughput

0.611

High

1076402

TRIP6
Thyroid receptor-interacting protein 6

2

18

High-throughput

0.606

High

1076871

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.586

High

1076910

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.586

High

324414

BAG3
BAG family molecular chaperone regulator 3

2

4

High-throughput

0.584

High

861768

PLK1
Serine/threonine-protein kinase PLK1

2

8

Small-scale

0.584

High

1027369

STK3
Serine/threonine-protein kinase 3

2

8

Small-scale

0.584

High

1041334

CUL2
Cullin-2

2

4

Small-scale

0.584

High

1076889

MOB1B
MOB kinase activator 1B

2

7

High-throughput

0.584

High

1076908

LLR1
Leucine-rich repeat protein 1

2

4

Small-scale

0.584

High

1076913

CSN4
COP9 signalosome complex subunit 4

2

4

Small-scale

0.584

High

1076925

MOB1A
MOB kinase activator 1A

2

7

High-throughput

0.584

High

1076895

RHPN1
Rhophilin-1

2

14

High-throughput

0.574

High

1076906

JPH4
Junctophilin-4

2

4

High-throughput

0.574

High

646918

1433T
14-3-3 protein theta

1

20

High-throughput

0.554

High

411734

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.553

High

901164

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.553

High

1070204

RAB35
Ras-related protein Rab-35

1

14

High-throughput

0.553

High

1076921

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

901674

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.536

High

1076946

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

4

High-throughput

0.536

High

830966

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.513

High

1076891

CRLF3
Cytokine receptor-like factor 3

1

0

High-throughput

0.513

High

661268

S10A2
Protein S100-A2

1

5

High-throughput

0.489

High

116837

KIF2A
Kinesin-like protein KIF2A

1

11

High-throughput

0.479

High

164383

TRI66
Tripartite motif-containing protein 66

1

4

High-throughput

0.479

High

171215

CTDSL
CTD small phosphatase-like protein

1

4

High-throughput

0.479

High

196443

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

4

High-throughput

0.479

High

216513

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

8

High-throughput

0.479

High

230876

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

6

High-throughput

0.479

High

237223

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.479

High

253356

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

17

High-throughput

0.479

High

305459

ZFPL1
Zinc finger protein-like 1

1

5

High-throughput

0.479

High

309961

ATE1
Arginyl-tRNA--protein transferase 1

1

1

High-throughput

0.479

High

374284

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

409086

K2C8
Keratin, type II cytoskeletal 8

1

2

High-throughput

0.479

High

418312

NPM
Nucleophosmin

1

3

High-throughput

0.479

High

475808

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

Small-scale

0.479

High

499771

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

542336

PLAK
Junction plakoglobin

1

20

Small-scale

0.479

High

552817

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

567071

CXA1
Gap junction alpha-1 protein

1

14

High-throughput

0.479

High

598480

NF1
Neurofibromin

1

10

High-throughput

0.479

High

647901

MARK3
MAP/microtubule affinity-regulating kinase 3

1

6

Small-scale

0.479

High

670040

MARCS
Myristoylated alanine-rich C-kinase substrate

1

10

High-throughput

0.479

High

672133

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

7

Small-scale

0.479

High

684056

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

684755

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

702767

CADH5
Cadherin-5

1

20

Small-scale

0.479

High

717111

CTNB1
Catenin beta-1

1

20

Small-scale

0.479

High

771981

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.479

High

822269

KC1D
Casein kinase I isoform delta

1

7

Small-scale

0.479

High

880738

HDAC4
Histone deacetylase 4

1

8

High-throughput

0.479

High

927815

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

Small-scale

0.479

High

940432

CXAR
Coxsackievirus and adenovirus receptor

1

18

High-throughput

0.479

High

983845

KPCZ
Protein kinase C zeta type

1

13

High-throughput

0.479

High

990848

ZO1
Tight junction protein ZO-1

1

20

Small-scale

0.479

High

1024164

CSN1
COP9 signalosome complex subunit 1

1

5

High-throughput

0.479

High

1041652

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1076867

ZYX
Zyxin

1

20

High-throughput

0.479

High

1076868

DDB1
DNA damage-binding protein 1

1

1

Small-scale

0.479

High

1076873

SPD2A
SH3 and PX domain-containing protein 2A

1

8

High-throughput

0.479

High

1076881

RBP10
Ran-binding protein 10

1

6

High-throughput

0.479

High

1076882

SYNE3
Nesprin-3

1

15

High-throughput

0.479

High

1076883

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.479

High

1076887

MOB3C
MOB kinase activator 3C

1

7

High-throughput

0.479

High

1076888

MAEA
E3 ubiquitin-protein transferase MAEA

1

10

High-throughput

0.479

High

1076890

MOB3B
MOB kinase activator 3B

1

7

High-throughput

0.479

High

1076892

ARMC8
Armadillo repeat-containing protein 8

1

4

High-throughput

0.479

High

1076896

BICD2
Protein bicaudal D homolog 2

1

9

High-throughput

0.479

High

1076899

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1076900

SRS12
Serine/arginine-rich splicing factor 12

1

1

High-throughput

0.479

High

1076901

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

7

High-throughput

0.479

High

1076904

MOB3A
MOB kinase activator 3A

1

7

High-throughput

0.479

High

1076905

BICD1
Protein bicaudal D homolog 1

1

9

High-throughput

0.479

High

1076907

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

7

High-throughput

0.479

High

1076917

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1076920

SAV1
Protein salvador homolog 1

1

20

High-throughput

0.479

High

1076922

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1076923

WDR26
WD repeat-containing protein 26

1

14

High-throughput

0.479

High

1076924

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

8

High-throughput

0.479

High

1076927

KI13B
Kinesin-like protein KIF13B

1

12

High-throughput

0.479

High

1076928

ANLN
Anillin

1

8

High-throughput

0.479

High

1076930

LATS2
Serine/threonine-protein kinase LATS2

1

13

High-throughput

0.479

High

1076931

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

4

High-throughput

0.479

High

1076932

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.479

High

1076933

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

1076936

HECW2
E3 ubiquitin-protein ligase HECW2

1

10

High-throughput

0.479

High

1076939

ZBT21
Zinc finger and BTB domain-containing protein 21

1

1

High-throughput

0.479

High

1076941

PPM1H
Protein phosphatase 1H

1

2

High-throughput

0.479

High

1076943

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

1076944

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

57681

A2BDD9
AMOT protein

1

15

High-throughput

0.470

High

992275

DPOE1
DNA polymerase epsilon catalytic subunit A

1

0

High-throughput

0.458

High

1060532

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

1076878

AMERL
AMMECR1-like protein

1

0

High-throughput

0.458

High

531475

K1C13
Keratin, type I cytoskeletal 13

1

1

High-throughput

0.445

High

679451

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

1

High-throughput

0.445

High

882317

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.445

High

118320

HAX1
HCLS1-associated protein X-1

1

2

High-throughput

0.437

High

132483

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

3

High-throughput

0.437

High

166562

DCLK1
Serine/threonine-protein kinase DCLK1

1

6

High-throughput

0.437

High

178547

STX7
Syntaxin-7

1

9

High-throughput

0.437

High

264313

GGYF1
GRB10-interacting GYF protein 1

1

5

High-throughput

0.437

High

279566

FLOT1
Flotillin-1

1

13

High-throughput

0.437

High

716689

CTNA1
Catenin alpha-1

1

5

Small-scale

0.437

High

793325

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.437

High

823404

PAXI
Paxillin

1

17

High-throughput

0.437

High

840479

VASP
Vasodilator-stimulated phosphoprotein

1

6

High-throughput

0.437

High

912920

ARF6
ADP-ribosylation factor 6

1

10

High-throughput

0.437

High

974838

CAV1
Caveolin-1

1

8

High-throughput

0.437

High

1076869

OCLN
Occludin

1

9

High-throughput

0.437

High

1076874

DEN4C
DENN domain-containing protein 4C

1

6

High-throughput

0.437

High

1076875

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.437

High

1076876

RNF43
E3 ubiquitin-protein ligase RNF43

1

20

High-throughput

0.437

High

1076879

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.437

High

1076880

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

1076884

SYDE1
Rho GTPase-activating protein SYDE1

1

19

High-throughput

0.437

High

1076897

BPIB1
BPI fold-containing family B member 1

1

3

High-throughput

0.437

High

1076898

DEN1A
DENN domain-containing protein 1A

1

7

High-throughput

0.437

High

1076902

CK052
Uncharacterized protein C11orf52

1

8

High-throughput

0.437

High

1076903

VP33A
Vacuolar protein sorting-associated protein 33A

1

5

High-throughput

0.437

High

1076912

RTKN
Rhotekin

1

1

High-throughput

0.437

High

1076916

NDEL1
Nuclear distribution protein nudE-like 1

1

7

High-throughput

0.437

High

1076919

DNJC5
DnaJ homolog subfamily C member 5

1

7

High-throughput

0.437

High

1076926

RC3H2
Roquin-2

1

10

High-throughput

0.437

High

1076934

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

13

High-throughput

0.437

High

1076935

CING
Cingulin

1

3

High-throughput

0.437

High

1076937

LIMA1
LIM domain and actin-binding protein 1

1

17

High-throughput

0.437

High

1076938

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

1076940

ANR50
Ankyrin repeat domain-containing protein 50

1

13

High-throughput

0.437

High

1076942

HECD1
E3 ubiquitin-protein ligase HECTD1

1

15

High-throughput

0.437

High

1076945

KCTD3
BTB/POZ domain-containing protein KCTD3

1

5

High-throughput

0.437

High

1076911

SCN2A
Sodium channel protein type 2 subunit alpha

1

10

High-throughput

0.407

High

159366

PLD2
Phospholipase D2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024