HitPredict

Interactor 1: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD

Interactor 2: ATG5 (Q99J83)
Autophagy protein 5 (APG5-like)
Gene: ATG5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	18946037, 22362782
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process GO:0032991 - protein-containing complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 205 Mm			1 275
+	Mm
		292703 CASP8_MOUSE (1-205): 1.55e-55: 184: 23.56		ATG5_MOUSE (1-275): 3.61e-147: 414: 100.00
+	Hs
		1026648 FADD_HUMAN (1-204): 3.64e-58: 183: 68.12		ATG5_HUMAN (1-275): 1.01e-146: 413: 96.73
+	Mm
		1141532 RIPK1_MOUSE (79-181): 1.16e-25: 105: 27.36		ATG5_MOUSE (1-275): 3.61e-147: 414: 100.00
+	Hs
		1038319 RIPK1_HUMAN (79-182): 2.28e-23: 98.7: 27.10		ATG5_HUMAN (1-275): 1.01e-146: 413: 96.73