HitPredict

Interactor 1: HIF1A (Q61221)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)
Gene: HIF1A

Interactor 2: FOXO3 (Q9WVH4)
Forkhead box protein O3
Gene: FOXO3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 18268343
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 836
Mm

1 672
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Ce
+ Ce
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024