HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33022573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 334
+	Hs
		452226 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		717431 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		965093 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		964960 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		WDR5_HUMAN (1-334): 3.63e-132: 381: 100.00
+	Hs
		717393 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49
+	Hs
		845305 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		LIS1_HUMAN (2-289): 9.62e-95: 288: 29.49
+	Hs
		1142339 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		POC1B_HUMAN (5-251): 2.76e-84: 264: 27.89
+	Hs
		1180234 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		SMU1_HUMAN (30-331): 7.69e-39: 145: 28.71
+	Hs
		1142287 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		SMU1_HUMAN (30-331): 7.69e-39: 145: 28.71