HitPredict

Interactor 1: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Interactor 2: MBD3 (Q9Z2D8)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26206133, 20362541
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001701 - in utero embryonic development GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 433 Mm			1 285
+	Hs
		328471 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		MBD3_HUMAN (1-267): 6.86e-158: 443: 97.75
+	Hs
		328481 RARA_HUMAN (38-430): 2.72e-111: 336: 27.64		MBD3_HUMAN (1-267): 6.86e-158: 443: 97.75
+	Hs
		370616 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		MBD2_HUMAN (4-253): 1.02e-134: 388: 75.20
+	Hs
		1069093 Q15156_HUMAN (101-430): 1.09e-111: 348: 30.51		MBD1_HUMAN (1-69): 6.78e-28: 114: 47.83
+	Hs
		370660 ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05		MBD1_HUMAN (1-69): 6.78e-28: 114: 47.83
+	Hs
		488032 RARA_HUMAN (38-430): 2.72e-111: 336: 27.64		MBD1_HUMAN (1-69): 6.78e-28: 114: 47.83