Protein: IF4E2
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3)

Gene: IF4E2, EIF4E2
Organism: Homo sapiens
Interactions: 238
UniProt ID: O60573

Gene Ontology (top 5):
GO:0000339 - RNA cap binding
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

237326

4ET
Eukaryotic translation initiation factor 4E transporter

7

2

Small-scale

0.971

High

237211

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

5

15

Small-scale

0.935

High

236378

4EBP3
Eukaryotic translation initiation factor 4E-binding protein 3

2

15

High-throughput

0.817

High

237212

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

2

15

High-throughput

0.811

High

237241

GGYF2
GRB10-interacting GYF protein 2

8

8

Small-scale

0.756

High

237145

GGYF1
GRB10-interacting GYF protein 1

7

8

Small-scale

0.754

High

237191

1433G
14-3-3 protein gamma

4

5

High-throughput

0.697

High

237203

1433F
14-3-3 protein eta

4

5

High-throughput

0.687

High

237357

ARI1
E3 ubiquitin-protein ligase ARIH1

2

3

Small-scale

0.636

High

237228

UBX11
UBX domain-containing protein 11

2

1

High-throughput

0.633

High

58210

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

2

1

High-throughput

0.628

High

237173

1433B
14-3-3 protein beta/alpha

2

5

High-throughput

0.628

High

124690

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

3

High-throughput

0.611

High

237194

1433Z
14-3-3 protein zeta/delta

2

5

High-throughput

0.611

High

237277

DI3L1
DIS3-like exonuclease 1

2

2

Small-scale

0.611

High

237306

WDR83
WD repeat domain-containing protein 83

3

2

High-throughput

0.609

High

237179

HD
Huntingtin

2

0

High-throughput

0.594

High

237193

1433E
14-3-3 protein epsilon

2

0

High-throughput

0.585

High

237260

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

1

High-throughput

0.584

High

237160

MYOG
Myogenin

2

1

High-throughput

0.573

High

237154

K1C19
Keratin, type I cytoskeletal 19

1

3

High-throughput

0.573

High

237159

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.573

High

237188

KR108
Keratin-associated protein 10-8

1

3

High-throughput

0.573

High

237189

KR109
Keratin-associated protein 10-9

1

3

High-throughput

0.573

High

237222

K1H1
Keratin, type I cuticular Ha1

1

5

High-throughput

0.573

High

237233

K1C40
Keratin, type I cytoskeletal 40

1

5

High-throughput

0.573

High

237310

TRI54
Tripartite motif-containing protein 54

1

5

High-throughput

0.573

High

237312

PRD14
PR domain zinc finger protein 14

1

1

High-throughput

0.573

High

237350

AMOL2
Angiomotin-like protein 2

1

1

High-throughput

0.573

High

237255

ZN598
E3 ubiquitin-protein ligase ZNF598

2

0

Small-scale

0.559

High

208079

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.549

High

237201

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.549

High

237202

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

237249

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.549

High

237251

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.549

High

237261

HOMEZ
Homeobox and leucine zipper protein Homez

1

0

High-throughput

0.549

High

237265

USBP1
Harmonin-binding protein USHBP1

1

0

High-throughput

0.549

High

237294

SPAG5
Sperm-associated antigen 5

1

0

High-throughput

0.549

High

237305

LZTS2
Leucine zipper putative tumor suppressor 2

1

0

High-throughput

0.549

High

237314

CARD9
Caspase recruitment domain-containing protein 9

1

0

High-throughput

0.549

High

237347

MARE3
Microtubule-associated protein RP/EB family member 3

1

0

High-throughput

0.549

High

237362

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.549

High

237176

K1C20
Keratin, type I cytoskeletal 20

1

4

High-throughput

0.541

High

237302

KR412
Keratin-associated protein 4-12

1

3

High-throughput

0.541

High

237299

MDFI
MyoD family inhibitor

1

0

High-throughput

0.536

High

207155

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

1

High-throughput

0.536

High

237164

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

237165

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

1

High-throughput

0.536

High

237167

1433T
14-3-3 protein theta

1

5

High-throughput

0.536

High

237172

S10A7
Protein S100-A7

1

1

High-throughput

0.536

High

237195

RACK1
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.536

High

237209

CDC16
Cell division cycle protein 16 homolog

1

1

High-throughput

0.536

High

237253

S1A7A
Protein S100-A7A

1

1

High-throughput

0.536

High

237286

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

237309

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

237322

EXOS5
Exosome complex component RRP46

1

4

High-throughput

0.536

High

237328

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.536

High

237240

ATL4
ADAMTS-like protein 4

1

2

High-throughput

0.523

High

237210

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.515

High

237356

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.515

High

237187

KR105
Keratin-associated protein 10-5

1

3

High-throughput

0.515

High

179991

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

237151

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

237182

ATX1
Ataxin-1

1

0

High-throughput

0.513

High

237234

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.513

High

237236

CAN13
Calpain-13

1

0

High-throughput

0.513

High

237268

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

237317

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

237323

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.513

High

237329

HOME3
Homer protein homolog 3

1

0

High-throughput

0.513

High

237148

ARI2
E3 ubiquitin-protein ligase ARIH2

1

3

Small-scale

0.501

High

237153

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

237300

EPAS1
Endothelial PAS domain-containing protein 1

1

1

Small-scale

0.500

High

237308

RBM4
RNA-binding protein 4

1

4

Small-scale

0.500

High

237298

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

237358

NGN3
Neurogenin-3

1

1

High-throughput

0.489

High

237158

K1C13
Keratin, type I cytoskeletal 13

1

4

High-throughput

0.481

High

237155

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

237273

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

162247

XPO1
Exportin-1

1

2

High-throughput

0.479

High

176891

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

3

High-throughput

0.479

High

216887

KIF1C
Kinesin-like protein KIF1C

1

2

High-throughput

0.479

High

230826

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

2

High-throughput

0.479

High

237144

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.479

High

237147

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

237150

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

237156

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

237163

NF1
Neurofibromin

1

1

High-throughput

0.479

High

237166

TTP
mRNA decay activator protein ZFP36

1

1

High-throughput

0.479

High

237170

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.479

High

237171

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

237174

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

237180

PRC2A
Protein PRRC2A

1

1

High-throughput

0.479

High

237183

AFAD
Afadin

1

3

High-throughput

0.479

High

237185

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.479

High

237186

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

237190

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

237192

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

237198

CDK16
Cyclin-dependent kinase 16

1

2

High-throughput

0.479

High

237199

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

237204

EXOS9
Exosome complex component RRP45

1

3

High-throughput

0.479

High

237207

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

1

High-throughput

0.479

High

237213

EXOS2
Exosome complex component RRP4

1

1

High-throughput

0.479

High

237215

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

4

Small-scale

0.479

High

237216

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.479

High

237217

UBP2L
Ubiquitin-associated protein 2-like

1

1

High-throughput

0.479

High

237218

MELK
Maternal embryonic leucine zipper kinase

1

1

High-throughput

0.479

High

237220

EXOS7
Exosome complex component RRP42

1

3

High-throughput

0.479

High

237221

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

237223

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.479

High

237226

EXOS6
Exosome complex component MTR3

1

5

High-throughput

0.479

High

237230

SPD2A
SH3 and PX domain-containing protein 2A

1

1

High-throughput

0.479

High

237231

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.479

High

237235

PKHA7
Pleckstrin homology domain-containing family A member 7

1

4

High-throughput

0.479

High

237238

LARP1
La-related protein 1

1

3

High-throughput

0.479

High

237244

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

237250

MYCPP
C-myc promoter-binding protein

1

2

High-throughput

0.479

High

237252

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

237258

MIB1
E3 ubiquitin-protein ligase MIB1

1

2

High-throughput

0.479

High

237259

KSR1
Kinase suppressor of Ras 1

1

1

High-throughput

0.479

High

237262

RPTOR
Regulatory-associated protein of mTOR

1

3

High-throughput

0.479

High

237270

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

2

High-throughput

0.479

High

237272

F110B
Protein FAM110B

1

1

High-throughput

0.479

High

237275

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.479

High

237278

HDAC7
Histone deacetylase 7

1

1

High-throughput

0.479

High

237280

SRS12
Serine/arginine-rich splicing factor 12

1

4

High-throughput

0.479

High

237285

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

237287

EXOS8
Exosome complex component RRP43

1

3

High-throughput

0.479

High

237293

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

1

High-throughput

0.479

High

237303

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

237315

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

237318

PKHA5
Pleckstrin homology domain-containing family A member 5

1

5

High-throughput

0.479

High

237320

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

3

High-throughput

0.479

High

237321

EXOS4
Exosome complex component RRP41

1

4

High-throughput

0.479

High

237324

KI13B
Kinesin-like protein KIF13B

1

2

High-throughput

0.479

High

237330

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

237336

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

237338

NGAP
Ras GTPase-activating protein nGAP

1

1

High-throughput

0.479

High

237339

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

High-throughput

0.479

High

237340

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.479

High

237346

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

2

High-throughput

0.479

High

237348

GAB2
GRB2-associated-binding protein 2

1

3

High-throughput

0.479

High

237349

NINL
Ninein-like protein

1

1

High-throughput

0.479

High

237352

EXOS1
Exosome complex component CSL4

1

2

High-throughput

0.479

High

237354

STA13
StAR-related lipid transfer protein 13

1

2

High-throughput

0.479

High

237355

HBS1L
HBS1-like protein

1

2

High-throughput

0.479

High

237359

RBM7
RNA-binding protein 7

1

3

High-throughput

0.479

High

237361

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

49544

A1A4E9
Keratin 13

1

4

High-throughput

0.470

High

122395

MEN1
Menin

1

0

High-throughput

0.458

High

154101

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.458

High

160276

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

196384

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.458

High

237142

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.458

High

237149

NADK
NAD kinase

1

0

High-throughput

0.458

High

237152

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

237162

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

237177

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

237178

MTREX
Exosome RNA helicase MTR4

1

0

High-throughput

0.458

High

237181

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.458

High

237196

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

0

Small-scale

0.458

High

237200

EXOSX
Exosome complex component 10

1

0

High-throughput

0.458

High

237206

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.458

High

237208

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

0

High-throughput

0.458

High

237214

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.458

High

237219

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

237229

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.458

High

237237

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.458

High

237242

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

237243

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

237254

PHLB2
Pleckstrin homology-like domain family B member 2

1

0

High-throughput

0.458

High

237257

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

0

High-throughput

0.458

High

237271

NAV1
Neuron navigator 1

1

0

High-throughput

0.458

High

237281

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

237282

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

237284

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

237289

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

237291

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

237292

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

237295

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.458

High

237297

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.458

High

237301

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

237307

RTKN
Rhotekin

1

0

High-throughput

0.458

High

237311

OSBL6
Oxysterol-binding protein-related protein 6

1

0

High-throughput

0.458

High

237316

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

237325

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

237327

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

0

High-throughput

0.458

High

237332

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.458

High

237333

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.458

High

237337

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.458

High

237342

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

237343

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

237345

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

0

High-throughput

0.458

High

237353

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

231408

KIF1B
Kinesin-like protein KIF1B

1

2

High-throughput

0.437

High

237184

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.437

High

237232

AN34A
Ankyrin repeat domain-containing protein 34A

1

3

High-throughput

0.437

High

237245

SYDE1
Rho GTPase-activating protein SYDE1

1

2

High-throughput

0.437

High

237247

ASXL2
Putative Polycomb group protein ASXL2

1

3

High-throughput

0.437

High

237248

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

237264

NIN
Ninein

1

1

High-throughput

0.437

High

237276

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

1

High-throughput

0.437

High

237279

DEP1B
DEP domain-containing protein 1B

1

1

High-throughput

0.437

High

237283

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

237319

TANC2
Protein TANC2

1

2

High-throughput

0.437

High

237239

CLC4G
C-type lectin domain family 4 member G

1

1

Small-scale

0.407

High

237288

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

0

High-throughput

0.327

High

237146

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.299

High

237161

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

237205

TLE5
TLE family member 5

1

0

High-throughput

0.299

High

237246

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.299

High

237266

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.299

High

237274

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

237157

PIP
Prolactin-inducible protein

1

0

High-throughput

0.279

Low

237168

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

237197

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

237227

CF141
Uncharacterized protein C6orf141

1

0

High-throughput

0.279

Low

237256

URP2
Fermitin family homolog 3

1

0

High-throughput

0.279

Low

237267

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

237290

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

237296

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

237313

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.279

Low

237341

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

237344

CELA1
Chymotrypsin-like elastase family member 1

1

0

High-throughput

0.279

Low

237143

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.251

Low

237225

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

166524

DCLK1
Serine/threonine-protein kinase DCLK1

1

0

High-throughput

0.249

Low

237169

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

237175

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

237224

TBC25
TBC1 domain family member 25

1

0

High-throughput

0.249

Low

237263

CCNQ
Cyclin-Q

1

0

High-throughput

0.249

Low

237269

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

237304

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.249

Low

237331

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

237334

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

237335

CING
Cingulin

1

0

High-throughput

0.249

Low

237351

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

237360

KCTD3
BTB/POZ domain-containing protein KCTD3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024