HitPredict

Interactor 1: LASP1 (Q61792)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Interactor 2: ZYX (Q62523)
Zyxin
Gene: ZYX

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15465019
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Mm			1 564
+	Hs
		1059978 LASP1_HUMAN (1-263): 8.1e-57: 184: 95.44		ZYX_HUMAN (1-564): 9.6e-68: 231: 85.19
+	Hs
		282335 NEBL_HUMAN (94-263): 2.51e-23: 101: 37.43		ZYX_HUMAN (1-564): 9.6e-68: 231: 85.19
+	Hs
		1080768 SRBS1_HUMAN (145-263): 5.6e-19: 88: 21.85		ZYX_HUMAN (1-564): 9.6e-68: 231: 85.19
+	Hs
		1078829 ITSN1_HUMAN (38-263): 2.37e-13: 71.8: 14.59		ZYX_HUMAN (1-564): 9.6e-68: 231: 85.19
+	Hs
		1080699 SH3R1_HUMAN (178-263): 2.68e-13: 71.2: 24.42		ZYX_HUMAN (1-564): 9.6e-68: 231: 85.19
+	Hs
		823513 ASAP1_HUMAN (36-263): 6.52e-23: 99.9: 13.10		PAXI_HUMAN (8-562): 8.44e-53: 191: 16.37
+	Hs
		823393 SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46		PAXI_HUMAN (8-562): 8.44e-53: 191: 16.37
+	Hs
		1060077 LASP1_HUMAN (1-263): 8.1e-57: 184: 95.44		TES_HUMAN (429-563): 9.43e-24: 105: 21.99
+	Hs
		823484 SRBS1_HUMAN (145-263): 5.6e-19: 88: 21.85		PAXI_HUMAN (8-562): 8.44e-53: 191: 16.37
+	Mm
		1143132 LASP1_MOUSE (1-263): 1.42e-59: 191: 100.00		LPP_MOUSE (4-487): 1.49e-15: 81.6: 15.52
+	Hs
		823431 SH3R1_HUMAN (178-263): 2.68e-13: 71.2: 24.42		PAXI_HUMAN (8-562): 8.44e-53: 191: 16.37
+	Hs
		1060028 LASP1_HUMAN (1-263): 8.1e-57: 184: 95.44		LPP_HUMAN (4-487): 4.26e-13: 73.9: 14.68
+	Hs
		1044592 LASP1_HUMAN (1-263): 8.1e-57: 184: 95.44		FHL3_HUMAN (402-536): 3.68e-09: 60.1: 28.99
+	Hs
		1355075 DBNL_HUMAN (75-263): 6.35e-34: 128: 24.23		TES_HUMAN (429-563): 9.43e-24: 105: 21.99
+	Hs
		1052344 SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46		TES_HUMAN (429-563): 9.43e-24: 105: 21.99
+	Hs
		596196 NEBU_HUMAN (15-263): 7.06e-24: 102: 27.30		LIMS1_HUMAN (390-536): 6.54e-09: 59.7: 26.80
+	Hs
		282330 NEBL_HUMAN (94-263): 2.51e-23: 101: 37.43		FHL3_HUMAN (402-536): 3.68e-09: 60.1: 28.99
+	Hs
		1050691 SH3R1_HUMAN (178-263): 2.68e-13: 71.2: 24.42		FHL2_HUMAN (460-564): 8.64e-19: 88.5: 23.81
+	Hs
		1078892 ITSN1_HUMAN (38-263): 2.37e-13: 71.8: 14.59		AJUBA_HUMAN (126-563): 5.11e-15: 80: 13.25
+	Hs
		1044619 CRIP3_HUMAN (5-54): 5.3e-15: 73.8: 38.00		FHL3_HUMAN (402-536): 3.68e-09: 60.1: 28.99