Protein: LTOR5
Ragulator complex protein LAMTOR5 (Hepatitis B virus X-interacting protein) (HBV X-interacting protein) (HBX-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5)

Gene: LTOR5, LAMTOR5
Organism: Homo sapiens
Interactions: 150
UniProt ID: O43504

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0008361 - regulation of cell size

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

206439

LTOR2
Ragulator complex protein LAMTOR2

5

0

Small-scale

0.880

High

206432

LTOR3
Ragulator complex protein LAMTOR3

3

0

Small-scale

0.787

High

206356

LTOR4
Ragulator complex protein LAMTOR4

8

0

Small-scale

0.723

High

206353

ZBT16
Zinc finger and BTB domain-containing protein 16

5

0

High-throughput

0.695

High

206395

CEP70
Centrosomal protein of 70 kDa

3

0

High-throughput

0.646

High

206385

RRAGA
Ras-related GTP-binding protein A

3

3

Small-scale

0.643

High

206423

RRAGC
Ras-related GTP-binding protein C

3

3

Small-scale

0.643

High

174254

TELT
Telethonin

3

0

High-throughput

0.639

High

206380

LTOR1
Ragulator complex protein LAMTOR1

3

0

Small-scale

0.638

High

206393

S38A9
Neutral amino acid transporter 9

3

0

Small-scale

0.638

High

206440

GIT1
ARF GTPase-activating protein GIT1

2

1

High-throughput

0.632

High

177629

BIRC5
Baculoviral IAP repeat-containing protein 5

3

0

Small-scale

0.625

High

206392

RPTOR
Regulatory-associated protein of mTOR

3

0

Small-scale

0.616

High

206348

EF1A1
Elongation factor 1-alpha 1

2

0

High-throughput

0.605

High

206379

RRAGB
Ras-related GTP-binding protein B

2

3

Small-scale

0.601

High

206425

RRAGD
Ras-related GTP-binding protein D

2

3

High-throughput

0.601

High

206367

NCOA6
Nuclear receptor coactivator 6

1

0

Small-scale

0.549

High

206329

MYF6
Myogenic factor 6

1

1

High-throughput

0.541

High

206364

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.541

High

206434

MKLN1
Muskelin

1

1

High-throughput

0.541

High

206315

P53
Cellular tumor antigen p53

1

0

Small-scale

0.537

High

206363

KEAP1
Kelch-like ECH-associated protein 1

1

0

Small-scale

0.537

High

206335

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.536

High

206357

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.536

High

206372

STK38
Serine/threonine-protein kinase 38

1

1

High-throughput

0.536

High

206398

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.536

High

206428

UBIP1
Upstream-binding protein 1

1

1

High-throughput

0.536

High

206437

ST38L
Serine/threonine-protein kinase 38-like

1

1

High-throughput

0.536

High

206442

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

1

High-throughput

0.536

High

206300

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.518

High

206314

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.518

High

206321

MYH3
Myosin-3

1

0

High-throughput

0.518

High

206328

SFPQ
Splicing factor, proline- and glutamine-rich

1

0

High-throughput

0.518

High

206330

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.518

High

206336

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.518

High

206340

AK1C2
Aldo-keto reductase family 1 member C2

1

0

High-throughput

0.518

High

206347

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.518

High

206362

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

206373

SHB
SH2 domain-containing adapter protein B

1

0

High-throughput

0.518

High

206387

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.518

High

206391

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

0

High-throughput

0.518

High

206406

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.518

High

206413

HTF4
Transcription factor 12

1

0

High-throughput

0.518

High

206417

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.518

High

206420

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

1

0

High-throughput

0.518

High

206421

ECT2
Protein ECT2

1

0

High-throughput

0.518

High

206443

SNX5
Sorting nexin-5

1

0

High-throughput

0.518

High

206435

UBQL1
Ubiquilin-1

1

1

High-throughput

0.515

High

179132

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.513

High

206301

RENR
Renin receptor

1

0

High-throughput

0.513

High

206302

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.513

High

206322

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

206334

HD
Huntingtin

1

0

High-throughput

0.513

High

206343

ALR
FAD-linked sulfhydryl oxidase ALR

1

0

High-throughput

0.513

High

206345

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

206349

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.513

High

206359

CDC16
Cell division cycle protein 16 homolog

1

0

High-throughput

0.513

High

206371

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

206382

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

1

0

High-throughput

0.513

High

206384

MOB2
MOB kinase activator 2

1

0

High-throughput

0.513

High

206386

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

206402

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

High-throughput

0.513

High

206410

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

206414

SORT
Sortilin

1

0

High-throughput

0.513

High

206415

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.513

High

206418

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.513

High

206424

GBA2
Non-lysosomal glucosylceramidase

1

0

High-throughput

0.513

High

206429

FNIP2
Folliculin-interacting protein 2

1

0

High-throughput

0.513

High

206436

TTF2
Transcription termination factor 2

1

0

High-throughput

0.513

High

206325

MYOG
Myogenin

1

1

High-throughput

0.494

High

206331

GRP75
Stress-70 protein, mitochondrial

1

1

High-throughput

0.494

High

206354

PPARA
Peroxisome proliferator-activated receptor alpha

1

2

High-throughput

0.494

High

206365

GIT2
ARF GTPase-activating protein GIT2

1

1

High-throughput

0.494

High

206390

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

2

High-throughput

0.494

High

206317

GELS
Gelsolin

1

0

High-throughput

0.493

High

206337

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

206341

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

206426

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

1

1

High-throughput

0.489

High

206305

RASN
GTPase NRas

1

2

High-throughput

0.479

High

206306

RASH
GTPase HRas

1

2

High-throughput

0.479

High

206307

RASK
GTPase KRas

1

2

High-throughput

0.479

High

206323

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

206324

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.479

High

206342

NR1H2
Oxysterols receptor LXR-beta

1

2

Small-scale

0.479

High

206344

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

206346

RAC1
Ras-related C3 botulinum toxin substrate 1

1

3

High-throughput

0.479

High

206351

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

206361

NR1H3
Oxysterols receptor LXR-alpha

1

2

Small-scale

0.479

High

206308

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

Small-scale

0.460

High

206311

ALBU
Albumin

1

0

Small-scale

0.460

High

206312

MT2
Metallothionein-2

1

0

Small-scale

0.460

High

206313

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

Small-scale

0.460

High

206352

TOP2B
DNA topoisomerase 2-beta

1

0

Small-scale

0.460

High

206375

GASP1
G-protein coupled receptor-associated sorting protein 1

1

0

High-throughput

0.460

High

206399

BHMT1
Betaine--homocysteine S-methyltransferase 1

1

0

Small-scale

0.460

High

206339

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.458

High

206350

E2F1
Transcription factor E2F1

1

0

Small-scale

0.458

High

206358

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.458

High

206360

STK4
Serine/threonine-protein kinase 4

1

0

Small-scale

0.458

High

206368

STAT4
Signal transducer and activator of transcription 4

1

0

Small-scale

0.458

High

206431

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

206401

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.439

High

206419

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.439

High

206403

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.438

High

206326

RHOQ
Rho-related GTP-binding protein RhoQ

1

3

High-throughput

0.437

High

206320

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

206332

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.426

High

206409

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.318

High

206338

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

206299

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.282

High

206316

ITB1
Integrin beta-1

1

0

High-throughput

0.282

High

206333

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.282

High

206388

ANR46
Ankyrin repeat domain-containing protein 46

1

0

High-throughput

0.282

High

206397

ZN592
Zinc finger protein 592

1

0

High-throughput

0.282

High

206427

CLIC5
Chloride intracellular channel protein 5

1

0

High-throughput

0.282

High

206430

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

206444

HEBP2
Heme-binding protein 2

1

0

High-throughput

0.282

High

203053

ERI3
ERI1 exoribonuclease 3

1

0

High-throughput

0.279

Low

206366

FHL2
Four and a half LIM domains protein 2

1

0

High-throughput

0.279

Low

206376

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.279

Low

206381

S18B1
MFS-type transporter SLC18B1

1

0

High-throughput

0.279

Low

206383

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.279

Low

206389

STX12
Syntaxin-12

1

0

High-throughput

0.279

Low

206396

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

206400

BORC5
BLOC-1-related complex subunit 5

1

0

High-throughput

0.279

Low

206404

BORC7
BLOC-1-related complex subunit 7

1

0

High-throughput

0.279

Low

206405

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

206407

BORC8
BLOC-1-related complex subunit 8

1

0

High-throughput

0.279

Low

206408

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

206416

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

206422

MTD2L
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial

1

0

High-throughput

0.279

Low

206433

TRM6
tRNA

1

0

High-throughput

0.279

Low

206438

SAC2
Phosphatidylinositide phosphatase SAC2

1

0

High-throughput

0.279

Low

206327

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

206355

Q0VDC6
peptidylprolyl isomerase

1

0

High-throughput

0.268

Low

206369

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

206441

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.268

Low

206303

CFAB
Complement factor B

1

0

Small-scale

0.251

Low

206304

A1AT
Alpha-1-antitrypsin

1

0

Small-scale

0.251

Low

206309

CO9
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]

1

0

Small-scale

0.251

Low

206310

RET4
Retinol-binding protein 4

1

0

Small-scale

0.251

Low

206318

ACBP
Acyl-CoA-binding protein

1

0

Small-scale

0.251

Low

206319

ASGR1
Asialoglycoprotein receptor 1

1

0

Small-scale

0.251

Low

206370

PDK1
[Pyruvate dehydrogenase

1

0

Small-scale

0.251

Low

206374

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.251

Low

206377

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

206394

MCPH1
Microcephalin

1

0

Small-scale

0.251

Low

206411

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.251

Low

206412

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.249

Low

206378

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024