HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: BAIP2 (Q8BKX1)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase 53 kDa substrate)
Gene: Baiap2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873, 36604605, 19455133
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0030165 - PDZ domain binding
GO:0035418 - protein localization to synapse
GO:0043005 - neuron projection
GO:0043197 - dendritic spine
GO:0044306 - neuron projection terminus
and 6 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 724
Mm

1 535
+ Hs
+ Rn
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024