Protein: K2C6A
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)

Gene: K2C6A, KRT6A
Organism: Homo sapiens
Interactions: 129
UniProt ID: P02538

Gene Ontology (top 5):
GO:0002009 - morphogenesis of an epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008284 - positive regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

359463

K1C15
Keratin, type I cytoskeletal 15

7

20

High-throughput

0.974

High

280939

KRT38
Keratin, type I cuticular Ha8

6

20

High-throughput

0.958

High

359503

K1C40
Keratin, type I cytoskeletal 40

5

20

High-throughput

0.942

High

359460

K1C13
Keratin, type I cytoskeletal 13

5

20

High-throughput

0.929

High

359496

K1H1
Keratin, type I cuticular Ha1

4

20

High-throughput

0.921

High

359482

K1C17
Keratin, type I cytoskeletal 17

2

20

High-throughput

0.785

High

280506

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

280766

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

359450

K1C18
Keratin, type I cytoskeletal 18

2

20

High-throughput

0.783

High

359453

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

359454

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

359509

K1C28
Keratin, type I cytoskeletal 28

2

20

High-throughput

0.783

High

359510

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

359511

K1C26
Keratin, type I cytoskeletal 26

2

20

High-throughput

0.783

High

359512

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

359519

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

359532

TRI54
Tripartite motif-containing protein 54

5

20

High-throughput

0.726

High

359529

KIFC3
Kinesin-like protein KIFC3

4

9

High-throughput

0.700

High

49547

A1A4E9
Keratin 13

1

20

High-throughput

0.700

High

359468

TRI23
E3 ubiquitin-protein ligase TRIM23

2

9

High-throughput

0.654

High

159834

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

5

High-throughput

0.646

High

359483

GOGA2
Golgin subfamily A member 2

4

7

High-throughput

0.644

High

359540

TFP11
Tuftelin-interacting protein 11

3

4

High-throughput

0.625

High

359446

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.621

High

359475

GEM
GTP-binding protein GEM

2

4

High-throughput

0.606

High

359531

BEX2
Protein BEX2

2

1

High-throughput

0.606

High

359497

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.582

High

359478

NCALD
Neurocalcin-delta

2

0

High-throughput

0.580

High

359544

UBQL2
Ubiquilin-2

2

0

High-throughput

0.580

High

213437

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

6

High-throughput

0.573

High

359469

NUP62
Nuclear pore glycoprotein p62

2

5

High-throughput

0.553

High

359514

TXLNB
Beta-taxilin

2

10

High-throughput

0.553

High

359485

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

High-throughput

0.541

High

359447

ALBU
Albumin

1

3

High-throughput

0.536

High

359458

CFTR
Cystic fibrosis transmembrane conductance regulator

1

16

High-throughput

0.536

High

359487

CUL1
Cullin-1

1

20

High-throughput

0.536

High

359488

CUL2
Cullin-2

1

20

High-throughput

0.536

High

359493

FL2D
Pre-mRNA-splicing regulator WTAP

1

7

High-throughput

0.536

High

359513

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

14

High-throughput

0.536

High

359521

CSN5
COP9 signalosome complex subunit 5

1

16

High-throughput

0.536

High

359522

CUL5
Cullin-5

1

20

High-throughput

0.536

High

359528

TCHP
Trichoplein keratin filament-binding protein

1

6

Small-scale

0.527

High

359508

POGZ
Pogo transposable element with ZNF domain

1

2

High-throughput

0.515

High

202807

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.513

High

231948

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.508

High

359547

WASC3
WASH complex subunit 3

1

2

High-throughput

0.494

High

359452

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.493

High

99725

F5H3M2
Kinesin-like protein

1

9

High-throughput

0.483

High

359502

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

12

High-throughput

0.481

High

124711

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

11

Small-scale

0.479

High

133822

DDX3X
ATP-dependent RNA helicase DDX3X

1

5

Small-scale

0.479

High

197172

SERA
D-3-phosphoglycerate dehydrogenase

1

6

Small-scale

0.479

High

233136

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

255412

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.479

High

267834

EED
Polycomb protein EED

1

11

High-throughput

0.479

High

282457

RNF8
E3 ubiquitin-protein ligase RNF8

1

13

High-throughput

0.479

High

301515

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

302762

HEXI1
Protein HEXIM1

1

18

High-throughput

0.479

High

325582

LATS1
Serine/threonine-protein kinase LATS1

1

6

High-throughput

0.479

High

345637

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

359448

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

359449

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

359451

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

3

Small-scale

0.479

High

359455

F16P1
Fructose-1,6-bisphosphatase 1

1

4

High-throughput

0.479

High

359456

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

7

High-throughput

0.479

High

359459

ITA4
Integrin alpha-4

1

3

High-throughput

0.479

High

359461

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

9

Small-scale

0.479

High

359462

DESP
Desmoplakin

1

20

Small-scale

0.479

High

359466

CBL
E3 ubiquitin-protein ligase CBL

1

11

High-throughput

0.479

High

359467

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

359470

EPS15
Epidermal growth factor receptor substrate 15

1

12

High-throughput

0.479

High

359471

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

359472

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.479

High

359476

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

359479

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.479

High

359480

GRB2
Growth factor receptor-bound protein 2

1

15

High-throughput

0.479

High

359484

TFCP2
Alpha-globin transcription factor CP2

1

4

High-throughput

0.479

High

359486

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

359489

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.479

High

359491

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.479

High

359494

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

6

High-throughput

0.479

High

359495

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

15

High-throughput

0.479

High

359498

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.479

High

359500

LARP7
La-related protein 7

1

11

High-throughput

0.479

High

359501

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

5

High-throughput

0.479

High

359504

PRP8
Pre-mRNA-processing-splicing factor 8

1

8

High-throughput

0.479

High

359505

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

359507

MEPCE
7SK snRNA methylphosphate capping enzyme

1

11

High-throughput

0.479

High

359516

PAPD5
Terminal nucleotidyltransferase 4B

1

3

High-throughput

0.479

High

359517

TNIP2
TNFAIP3-interacting protein 2

1

4

High-throughput

0.479

High

359518

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

20

High-throughput

0.479

High

359520

HDAC2
Histone deacetylase 2

1

12

High-throughput

0.479

High

359523

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

7

Small-scale

0.479

High

359525

AP2M1
AP-2 complex subunit mu

1

8

High-throughput

0.479

High

359526

RNF31
E3 ubiquitin-protein ligase RNF31

1

16

High-throughput

0.479

High

359535

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

359536

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

359537

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

10

High-throughput

0.479

High

359538

ANLN
Anillin

1

11

High-throughput

0.479

High

359541

HDAC6
Histone deacetylase 6

1

12

High-throughput

0.479

High

359543

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

359545

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

165899

PER2
Period circadian protein homolog 2

1

0

Small-scale

0.458

High

277871

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

High-throughput

0.458

High

322050

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

337731

EGFR
Epidermal growth factor receptor

1

7

Small-scale

0.445

High

353600

IGHG1
Immunoglobulin heavy constant gamma 1

1

7

High-throughput

0.445

High

359457

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

359464

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.445

High

359477

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

359481

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.445

High

359490

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.445

High

359534

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

359533

TSG10
Testis-specific gene 10 protein

1

7

High-throughput

0.439

High

359465

EFNA1
Ephrin-A1

1

20

High-throughput

0.437

High

359473

EFNA3
Ephrin-A3

1

20

High-throughput

0.437

High

359474

EFNA4
Ephrin-A4

1

20

High-throughput

0.437

High

359492

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

2

High-throughput

0.437

High

359499

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

3

Small-scale

0.437

High

359506

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

359527

DIRA2
GTP-binding protein Di-Ras2

1

2

Small-scale

0.437

High

359530

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

6

High-throughput

0.437

High

359539

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

359542

KS6B2
Ribosomal protein S6 kinase beta-2

1

8

High-throughput

0.437

High

359546

AAR2
Protein AAR2 homolog

1

6

High-throughput

0.437

High

877

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.407

High

103485

G4U4J3
PAP associated domain containing 5

1

3

High-throughput

0.407

High

359515

MOT11
Monocarboxylate transporter 11

1

3

High-throughput

0.407

High

359524

PP14B
Protein phosphatase 1 regulatory subunit 14B

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024