Interactor 1: IRAK1 (Q62406)
Interleukin-1 receptor-associated kinase 1 (IRAK) (IRAK-1) (EC 2.7.11.1) (Pelle-like protein kinase) (mPLK)
Gene: IRAK1

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 18562480, 21911421
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007254 - JNK cascade
GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0032496 - response to lipopolysaccharide
GO:0034142 - toll-like receptor 4 signaling pathway
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 710
Mm

1 835
+ Hs
+ At
+ At
+ At
+ At
+ At
+ At
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+ At
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+ Mm
+ At
+ At
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+ Hs
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+ At

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Last updated: 15 Jul 2024