HitPredict

Interactor 1: SH3G1 (Q62419)
Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) (SH3p8)
Gene: Sh3gl1

Interactor 2: PDC6I (Q9WU78)
Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2)
Gene: Pdcd6ip

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	12034747
Identification Methods	two hybrid, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 368 Mm			1 869
+	Hs
		1260385 SH3G1_HUMAN (1-368): 9.68e-90: 276: 94.02		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Hs
		1260386 SH3G2_HUMAN (1-368): 7.3e-84: 260: 69.02		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Mm
		1143926 SH3G2_MOUSE (1-368): 2.76e-83: 259: 68.48		PDC6I_MOUSE (1-869): 0: 773: 100.00
+	Mm
		1208610 PLCG2_MOUSE (42-363): 7.37e-34: 135: 13.11		PDC6I_MOUSE (1-869): 0: 773: 100.00
+	Hs
		1191850 SH3R1_HUMAN (305-361): 2.12e-12: 70.6: 45.90		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Hs
		924726 GRB2_HUMAN (311-367): 1.14e-11: 65.6: 39.66		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Ce
		70028 SH3GH_CAEEL (1-367): 2.22e-70: 226: 43.60		ALXA_CAEEL (4-834): 0: 626: 37.37
+	Hs
		1078881 ITSN1_HUMAN (199-366): 2.34e-10: 64.3: 13.87		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Mm
		1141174 GRB2_MOUSE (311-367): 1.14e-11: 65.6: 39.66		PDC6I_MOUSE (1-869): 0: 773: 100.00
+	Hs
		1307434 SH3G2_HUMAN (1-368): 7.3e-84: 260: 69.02		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Dm
		1180080 Q7K4D1_DROME (309-367): 7.07e-10: 62.8: 47.46		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Dm
		1342129 Q9NHP2_DROME (309-367): 7.07e-10: 62.8: 47.46		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Ce
		666203 SEM5_CAEEL (312-360): 2.61e-11: 64.7: 53.06		ALXA_CAEEL (4-834): 0: 626: 37.37
+	Hs
		924858 GRB2_HUMAN (311-367): 1.14e-11: 65.6: 39.66		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Hs
		1078907 ITSN1_HUMAN (199-366): 2.34e-10: 64.3: 13.87		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Dm
		993211 GRAP_DROME (284-360): 2.61e-11: 64.3: 46.75		Q9VUH6_DROME (4-866): 7.61e-144: 468: 21.43
+	Mm
		101448 SH3G1_MOUSE (1-368): 2.23e-89: 275: 100.00		F8VPR5_MOUSE (632-866): 1.16e-25: 116: 16.91
+	Hs
		1307452 SH3G3_HUMAN (1-368): 4.4e-87: 268: 66.30		WDR33_HUMAN (671-867): 4.66e-10: 65.7: 13.33
+	Ce
		70017 SH3GH_CAEEL (1-367): 2.22e-70: 226: 43.60		G5EBN5_CAEEL (433-867): 3.02e-10: 66.5: 12.73
+	Hs
		159946 GRB2_HUMAN (311-367): 1.14e-11: 65.6: 39.66		HGS_HUMAN (550-863): 3.74e-27: 120: 18.10