HitPredict

Interactor 1: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Interactor 2: HS904 (Q58FG1)
Putative heat shock protein HSP 90-alpha A4 (Heat shock 90 kDa protein 1 alpha-like 2) (Heat shock protein 90-alpha D) (Heat shock protein 90Ad)
Gene: HSP90AA4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CS~HATPase_c_3
Common GO terms	GO:0051082 - unfolded protein binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 418
+	Hs
		461497 TEBP_HUMAN (1-160): 4.37e-55: 172: 100.00		HS90A_HUMAN (89-277): 7.79e-49: 178: 48.42
+	Hs
		468393 TEBP_HUMAN (1-160): 4.37e-55: 172: 100.00		HS90B_HUMAN (89-256): 3.15e-44: 165: 49.70
+	Mm
		547285 TEBP_MOUSE (1-160): 2.51e-54: 170: 98.75		HS90B_MOUSE (89-256): 3.54e-44: 165: 49.70
+	Hs
		573485 TEBP_HUMAN (1-160): 4.37e-55: 172: 100.00		ENPL_HUMAN (95-407): 8.59e-39: 150: 26.81
+	Hs
		1144012 TEBP_HUMAN (1-160): 4.37e-55: 172: 100.00		H90B4_HUMAN (112-275): 1.79e-26: 112: 42.42
+	Sc
		392356 SBA1_YEAST (3-140): 3.47e-28: 105: 22.37		HSP82_YEAST (96-256): 1.98e-43: 163: 43.83
+	Sc
		578976 SBA1_YEAST (3-140): 3.47e-28: 105: 22.37		HSC82_YEAST (96-256): 3.97e-43: 162: 43.83
+	Hs
		1144037 TEBP_HUMAN (1-160): 4.37e-55: 172: 100.00		Q6PK50_HUMAN (89-157): 1.44e-15: 79.3: 55.71