HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0008017 - microtubule binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 2028
+	Hs
		1113789 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		1113782 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		GRDN_HUMAN (6-1787): 2.69e-103: 371: 47.30
+	Hs
		1145917 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CP250_HUMAN (613-1708): 8.43e-35: 149: 11.02
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		1113839 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		CP250_HUMAN (613-1708): 8.43e-35: 149: 11.02
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		1113802 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		HOOK3_HUMAN (4-548): 2.59e-25: 116: 24.56
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		725198 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		HOOK3_HUMAN (4-548): 2.59e-25: 116: 24.56
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (942-1722): 7.95e-26: 119: 9.30
+	Hs
		724687 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (1047-1683): 1.07e-23: 112: 9.66
+	Hs
		528435 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH4_HUMAN (1093-1725): 3.21e-17: 90.9: 8.68
+	Hs
		725189 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH14_HUMAN (941-1430): 7.1e-15: 83.1: 16.06
+	Hs
		502933 MYH3_HUMAN (474-1140): 7.75e-35: 147: 14.20		MYH4_HUMAN (1093-1725): 3.21e-17: 90.9: 8.68
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (145-597): 5.04e-12: 73.8: 14.32