Protein: HMBX1
Homeobox-containing protein 1 (Homeobox telomere-binding protein 1) (Telomere-associated homeobox-containing protein 1)

Gene: HMBX1, HMBOX1
Organism: Homo sapiens
Interactions: 145
UniProt ID: Q6NT76

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003691 - double-stranded telomeric DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1156022

HMBX1
Homeobox-containing protein 1

3

13

High-throughput

0.861

High

180990

GSC2
Homeobox protein goosecoid-2

2

19

High-throughput

0.783

High

641447

PAX6
Paired box protein Pax-6

2

15

High-throughput

0.783

High

837812

MEOX1
Homeobox protein MOX-1

2

20

High-throughput

0.783

High

1131046

VAX1
Ventral anterior homeobox 1

2

19

High-throughput

0.783

High

1156060

ASB7
Ankyrin repeat and SOCS box protein 7

5

0

High-throughput

0.694

High

515600

SRF
Serum response factor

1

4

High-throughput

0.691

High

1156041

DYL2
Dynein light chain 2, cytoplasmic

3

2

High-throughput

0.675

High

875651

MFAP1
Microfibrillar-associated protein 1

3

1

High-throughput

0.675

High

1156023

AEBP2
Zinc finger protein AEBP2

3

14

High-throughput

0.675

High

1156034

ZN417
Zinc finger protein 417

3

1

High-throughput

0.675

High

1156039

KAT5
Histone acetyltransferase KAT5

3

1

High-throughput

0.675

High

1156061

SH24A
SH2 domain-containing protein 4A

3

8

High-throughput

0.675

High

1156067

CBX8
Chromobox protein homolog 8

3

2

High-throughput

0.675

High

1156077

ZN581
Zinc finger protein 581

3

6

High-throughput

0.675

High

1156079

MO4L1
Mortality factor 4-like protein 1

3

1

High-throughput

0.675

High

585918

WT1
Wilms tumor protein

3

4

High-throughput

0.667

High

928340

DYL1
Dynein light chain 1, cytoplasmic

3

2

High-throughput

0.665

High

1151072

Q6FHY5
MEOX2 protein

1

20

High-throughput

0.665

High

702082

RL9
Large ribosomal subunit protein uL6

3

0

High-throughput

0.646

High

1046862

BYST
Bystin

3

0

High-throughput

0.646

High

1107875

F161A
Protein FAM161A

3

0

High-throughput

0.646

High

1156074

ABITM
Protein Abitram

3

0

High-throughput

0.646

High

985224

HME1
Homeobox protein engrailed-1

1

19

High-throughput

0.646

High

1156084

MEMO1
Protein MEMO1

3

0

High-throughput

0.638

High

1156051

SCNM1
Sodium channel modifier 1

3

0

High-throughput

0.622

High

838055

MEOX2
Homeobox protein MOX-2

1

20

High-throughput

0.621

High

125895

CDC7
Cell division cycle 7-related protein kinase

2

6

High-throughput

0.606

High

278294

PIAS2
E3 SUMO-protein ligase PIAS2

2

1

High-throughput

0.606

High

297177

IPO13
Importin-13

2

6

High-throughput

0.606

High

319231

BRD1
Bromodomain-containing protein 1

2

13

High-throughput

0.606

High

549185

ZN250
Zinc finger protein 250

2

2

High-throughput

0.606

High

638516

RBTN1
Rhombotin-1

2

7

High-throughput

0.606

High

641823

U2AF2
Splicing factor U2AF 65 kDa subunit

2

1

High-throughput

0.606

High

971662

PAX5
Paired box protein Pax-5

2

15

High-throughput

0.606

High

989690

CDK18
Cyclin-dependent kinase 18

2

11

High-throughput

0.606

High

1062999

MO4L2
Mortality factor 4-like protein 2

2

1

High-throughput

0.606

High

1075112

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.606

High

1148017

ZFY26
Zinc finger FYVE domain-containing protein 26

2

4

High-throughput

0.606

High

1156032

GA2L2
GAS2-like protein 2

2

3

High-throughput

0.606

High

1156033

LMO3
LIM domain only protein 3

2

7

High-throughput

0.606

High

1156040

MCRS1
Microspherule protein 1

2

1

High-throughput

0.606

High

1156057

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

2

5

High-throughput

0.606

High

1156068

ZBT26
Zinc finger and BTB domain-containing protein 26

2

3

High-throughput

0.606

High

1156070

PICK1
PRKCA-binding protein

2

1

High-throughput

0.606

High

1156078

RCOR3
REST corepressor 3

2

16

High-throughput

0.606

High

1156081

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

2

20

High-throughput

0.606

High

1156082

ZMYM5
Zinc finger MYM-type protein 5

2

6

High-throughput

0.606

High

132904

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

920481

RS25
Small ribosomal subunit protein eS25

2

0

High-throughput

0.580

High

1039631

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.580

High

1121602

BOREA
Borealin

2

0

High-throughput

0.580

High

1134910

SYT6
Synaptotagmin-6

2

0

High-throughput

0.580

High

1156027

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.580

High

1156038

FGF11
Fibroblast growth factor 11

2

0

High-throughput

0.580

High

1156047

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.580

High

1156055

IN80B
INO80 complex subunit B

2

0

High-throughput

0.580

High

1156056

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.580

High

1156066

KIF9
Kinesin-like protein KIF9

2

0

High-throughput

0.580

High

1156071

F217B
Protein FAM217B

2

0

High-throughput

0.580

High

1156072

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

0

High-throughput

0.580

High

1156080

DPOLL
DNA polymerase lambda

2

0

High-throughput

0.580

High

48118

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

3

High-throughput

0.573

High

196626

ZBT24
Zinc finger and BTB domain-containing protein 24

1

4

High-throughput

0.573

High

269156

DAB1
Disabled homolog 1

1

2

High-throughput

0.573

High

311935

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.573

High

441314

RU2B
U2 small nuclear ribonucleoprotein B''

1

1

High-throughput

0.573

High

816019

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.573

High

844111

FXR2
RNA-binding protein FXR2

1

1

High-throughput

0.573

High

851782

CCNG1
Cyclin-G1

1

4

High-throughput

0.573

High

871411

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

3

High-throughput

0.573

High

942418

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

1

High-throughput

0.573

High

1025152

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

3

High-throughput

0.573

High

1156030

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

1

1

High-throughput

0.573

High

1156044

FRMD6
FERM domain-containing protein 6

1

3

High-throughput

0.573

High

1156046

ZN587
Zinc finger protein 587

1

1

High-throughput

0.573

High

1156058

MAGH1
Melanoma-associated antigen H1

1

1

High-throughput

0.573

High

1156059

CARD9
Caspase recruitment domain-containing protein 9

1

2

High-throughput

0.573

High

1156086

ZN337
Zinc finger protein 337

1

1

High-throughput

0.573

High

360048

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

6

High-throughput

0.571

High

1023876

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.549

High

1079874

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.549

High

1156025

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.549

High

1156035

LNX1
E3 ubiquitin-protein ligase LNX

1

0

High-throughput

0.549

High

1156042

REEP6
Receptor expression-enhancing protein 6

1

0

High-throughput

0.549

High

1156043

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.549

High

1156063

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

0

High-throughput

0.549

High

1156065

SP30L
Histone deacetylase complex subunit SAP30L

1

0

High-throughput

0.549

High

157050

AIM2
Interferon-inducible protein AIM2

1

2

High-throughput

0.536

High

638989

S100P
Protein S100-P

1

4

High-throughput

0.536

High

988946

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.536

High

1153847

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.536

High

1156037

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.536

High

46647

A0A384ME17
Elongation factor Tu

1

1

High-throughput

0.515

High

1103931

Q32MN6
TATA-box-binding protein

1

5

High-throughput

0.515

High

1156024

Q7KZS0
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.515

High

64242

ZAR1L
Protein ZAR1-like

1

0

High-throughput

0.513

High

1156049

DCC1
Sister chromatid cohesion protein DCC1

1

0

High-throughput

0.513

High

1156083

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

394943

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

242493

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

Small-scale

0.500

High

523822

XRCC6
X-ray repair cross-complementing protein 6

1

8

Small-scale

0.500

High

473674

ZN688
Zinc finger protein 688

1

7

High-throughput

0.481

High

589886

TBP
TATA-box-binding protein

1

5

High-throughput

0.481

High

827435

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.481

High

930264

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

1156053

PDIP3
Polymerase delta-interacting protein 3

1

3

High-throughput

0.481

High

717162

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

727540

HNF1B
Hepatocyte nuclear factor 1-beta

1

15

High-throughput

0.479

High

749595

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

917446

H4
Histone H4

1

3

High-throughput

0.479

High

1000190

IFFO1
Non-homologous end joining factor IFFO1

1

7

High-throughput

0.479

High

1018535

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

17

High-throughput

0.479

High

1018991

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

1056866

MDC1
Mediator of DNA damage checkpoint protein 1

1

20

High-throughput

0.479

High

1156028

AMOL1
Angiomotin-like protein 1

1

4

High-throughput

0.479

High

1156045

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

49708

A1A5B0
ANKRD36 protein

1

2

High-throughput

0.470

High

1156036

Q8WUT1
POLDIP3 protein

1

2

High-throughput

0.470

High

1156052

CDAC1
Cytidine and dCMP deaminase domain-containing protein 1

1

0

High-throughput

0.458

High

524958

XRCC5
X-ray repair cross-complementing protein 5

1

8

Small-scale

0.445

High

750312

COIL
Coilin

1

1

Small-scale

0.445

High

1043874

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.445

High

1156064

LN28A
Protein lin-28 homolog A

1

1

High-throughput

0.445

High

1156069

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

1

Small-scale

0.445

High

1156073

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

3

Small-scale

0.445

High

1156075

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

Small-scale

0.445

High

1156076

GRHL1
Grainyhead-like protein 1 homolog

1

5

High-throughput

0.445

High

64309

AN36A
Ankyrin repeat domain-containing protein 36A

1

2

High-throughput

0.439

High

1121920

COBL1
Cordon-bleu protein-like 1

1

9

High-throughput

0.437

High

484146

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

3408

A0A0S2Z5X4
Zinc finger protein 688 isoform 4

1

6

High-throughput

0.417

High

1156062

CH033
UPF0488 protein C8orf33

3

0

High-throughput

0.352

High

1110164

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1156026

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1156029

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

1156031

FA13C
Protein FAM13C

1

0

High-throughput

0.299

High

1156050

FND11
Fibronectin type III domain-containing protein 11

1

0

High-throughput

0.299

High

1156085

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.299

High

1156087

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.282

High

92529

NPIA7
Nuclear pore complex-interacting protein family member A7

1

0

High-throughput

0.268

Low

1137118

FAM74
Protein FAM74A4/A6

1

0

High-throughput

0.268

Low

1156048

SELS
Selenoprotein S

1

0

High-throughput

0.249

Low

1156054

F117A
Protein FAM117A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024