HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: CP131 (Q9UPN4)
Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)
Gene: CEP131

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 26496610, 34079125
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 1083
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (115-657): 3.26e-14: 79.9: 9.29
+	Hs
		1146002 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MRCKB_HUMAN (228-728): 8.99e-12: 72: 11.27
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (239-1083): 1.05e-33: 143: 10.00
+	Dd
		445145 MYS2_DICDI (1-1088): 1.21e-53: 208: 12.19		MYS2_DICDI (598-1083): 2.83e-17: 89.9: 12.78
+	Hs
		724687 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH9_HUMAN (117-841): 6.25e-23: 108: 9.26
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (407-1083): 1.56e-23: 110: 11.54
+	Hs
		675177 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		CLIP1_HUMAN (56-826): 1.34e-18: 94.2: 8.40
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (401-1083): 1.84e-23: 110: 10.69
+	Hs
		1068548 GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61		PLEC_HUMAN (237-915): 7.61e-17: 88.6: 13.48
+	Hs
		528435 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (115-657): 3.26e-14: 79.9: 9.29
+	Rn
		361106 MYH6_RAT (474-1128): 1.63e-33: 143: 14.31		MYH6_RAT (401-1083): 3.47e-23: 109: 10.69
+	Hs
		502933 MYH3_HUMAN (474-1140): 7.75e-35: 147: 14.20		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (115-657): 3.26e-14: 79.9: 9.29
+	Hs
		522585 MYH7_HUMAN (588-1139): 1.75e-29: 129: 11.94		MYH7_HUMAN (454-1078): 2.77e-22: 106: 13.38
+	Mm
		93570 DESP_MOUSE (212-1059): 2.19e-26: 120: 14.43		MYH9_MOUSE (117-841): 8.48e-25: 114: 9.85
+	Hs
		522657 MYH7_HUMAN (588-1139): 1.75e-29: 129: 11.94		MYH4_HUMAN (454-1054): 3.45e-20: 99.5: 11.86