HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30196744, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 543
+	Hs
		826710 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821259 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573308 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		1306704 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		921697 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		921038 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		821355 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573412 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		792942 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826605 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826604 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821437 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821157 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821156 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573205 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		573204 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843411 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843145 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843144 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Mm
		516947 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		TCPA_MOUSE (14-528): 2.94e-88: 284: 35.20