HitPredict

Interactor 1: SIZ1 (Q680Q4)
E3 SUMO-protein ligase SIZ1 (EC 2.3.2.-) (E3 SUMO-protein transferase SIZ1)
Gene: SIZ1

Interactor 2: SUMO2 (Q9FLP6)
Small ubiquitin-related modifier 2 (AtSUMO2)
Gene: SUMO2

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	24255109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~zf-MIZ
Common GO terms	GO:0005634 - nucleus GO:0016925 - protein sumoylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 884 At			1 103
+	At
		878961 SIZ1_ARATH (1-884): 0: 985: 100.00		SUMO1_ARATH (1-90): 1.93e-35: 118: 93.41
+	At
		1147333 SIZ1_ARATH (1-884): 0: 985: 100.00		SUMO3_ARATH (3-96): 7.7e-35: 117: 50.00
+	Sc
		978700 SIZ1_YEAST (2-860): 1.91e-159: 491: 14.97		SMT3_YEAST (3-93): 4.52e-32: 109: 45.06
+	Hs
		278250 PIAS2_HUMAN (1-587): 1.2e-153: 466: 19.51		SUMO3_HUMAN (4-98): 1.41e-39: 128: 50.53
+	Hs
		278253 PIAS2_HUMAN (1-587): 1.2e-153: 466: 19.51		SUMO2_HUMAN (4-93): 1.33e-39: 128: 52.22
+	Rn
		1140374 PIAS2_RAT (1-563): 1.89e-151: 459: 19.97		SUMO3_RAT (4-97): 1.76e-39: 128: 51.06
+	Hs
		278256 PIAS2_HUMAN (1-587): 1.2e-153: 466: 19.51		SUMO1_HUMAN (3-92): 9.71e-35: 116: 45.56
+	Hs
		102147 PIAS2_HUMAN (1-587): 1.2e-153: 466: 19.51		SUMO5_HUMAN (3-92): 2.55e-34: 115: 42.22
+	Hs
		879167 PIAS3_HUMAN (1-658): 1.75e-146: 448: 18.34		SUMO3_HUMAN (4-98): 1.41e-39: 128: 50.53
+	Hs
		902827 PIAS3_HUMAN (1-658): 1.75e-146: 448: 18.34		SUMO2_HUMAN (4-93): 1.33e-39: 128: 52.22
+	Mm
		222291 PIAS3_MOUSE (1-658): 1.58e-147: 451: 17.90		SUMO1_MOUSE (3-92): 9.71e-35: 116: 45.56
+	Hs
		928241 PIAS3_HUMAN (1-658): 1.75e-146: 448: 18.34		SUMO1_HUMAN (3-92): 9.71e-35: 116: 45.56
+	Hs
		278009 PIAS1_HUMAN (1-624): 1.93e-140: 433: 18.67		SUMO3_HUMAN (4-98): 1.41e-39: 128: 50.53
+	Hs
		278020 PIAS1_HUMAN (1-624): 1.93e-140: 433: 18.67		SUMO2_HUMAN (4-93): 1.33e-39: 128: 52.22
+	Hs
		278040 PIAS1_HUMAN (1-624): 1.93e-140: 433: 18.67		SUMO1_HUMAN (3-92): 9.71e-35: 116: 45.56
+	Hs
		102146 PIAS1_HUMAN (1-624): 1.93e-140: 433: 18.67		SUMO5_HUMAN (3-92): 2.55e-34: 115: 42.22
+	Hs
		879136 PIAS4_HUMAN (6-483): 8.79e-135: 414: 19.51		SUMO3_HUMAN (4-98): 1.41e-39: 128: 50.53
+	Hs
		902668 PIAS4_HUMAN (6-483): 8.79e-135: 414: 19.51		SUMO2_HUMAN (4-93): 1.33e-39: 128: 52.22
+	Hs
		928135 PIAS4_HUMAN (6-483): 8.79e-135: 414: 19.51		SUMO1_HUMAN (3-92): 9.71e-35: 116: 45.56
+	Sc
		1015324 SIZ2_YEAST (16-769): 5.05e-132: 414: 14.71		SMT3_YEAST (3-93): 4.52e-32: 109: 45.06