HitPredict

Interactor 1: NR3L1 (Q68D85)
Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6)
Gene: NCR3LG1

Interactor 2: RAE1E (Q8TD07)
Retinoic acid early transcript 1E (Lymphocyte effector toxicity activation ligand) (NKG2D ligand 4) (N2DL-4) (NKG2DL4) (RAE-1-like transcript 4) (UL16-binding protein 4)
Gene: RAET1E

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~MHC_I
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 263
+	Hs
		1100231 NR3L1_HUMAN (1-454): 1.09e-146: 427: 100.00		MICA_HUMAN (10-210): 5.3e-14: 72.8: 26.70
+	Hs
		69945 TPSNR_HUMAN (2-275): 1.18e-32: 130: 21.43		B1PKZ2_HUMAN (7-254): 3.27e-116: 339: 20.87
+	Hs
		182246 TPSN_HUMAN (19-293): 2.7e-33: 132: 18.40		HLAA_HUMAN (7-254): 2.28e-114: 334: 21.26
+	Hs
		382512 TPSNR_HUMAN (2-275): 1.18e-32: 130: 21.43		HLAA_HUMAN (7-254): 2.28e-114: 334: 21.26
+	Hs
		182242 TPSN_HUMAN (19-293): 2.7e-33: 132: 18.40		HLAB_HUMAN (6-254): 1.83e-111: 327: 21.57
+	Hs
		354547 TPSNR_HUMAN (2-275): 1.18e-32: 130: 21.43		HLAB_HUMAN (6-254): 1.83e-111: 327: 21.57
+	Hs
		382258 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		HLAA_HUMAN (7-254): 2.28e-114: 334: 21.26
+	Hs
		382299 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		HLAG_HUMAN (6-254): 2.7e-112: 328: 21.18
+	Hs
		354248 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		HLAB_HUMAN (6-254): 1.83e-111: 327: 21.57
+	Hs
		182250 TPSN_HUMAN (19-293): 2.7e-33: 132: 18.40		HLAC_HUMAN (7-254): 1.54e-106: 314: 20.87
+	Hs
		488114 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		HLAC_HUMAN (7-254): 1.54e-106: 314: 20.87
+	Hs
		382277 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		HLAC_HUMAN (7-254): 1.54e-106: 314: 20.87
+	Mm
		354643 TPSN_MOUSE (29-256): 2.75e-31: 126: 17.93		HA11_MOUSE (8-253): 1.65e-103: 306: 21.83
+	Hs
		545166 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		ULBP3_HUMAN (29-235): 5.24e-99: 291: 41.04
+	Hs
		382286 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		HLAE_HUMAN (24-252): 1.73e-98: 293: 19.15
+	Hs
		1166301 BTNL8_HUMAN (24-289): 3.71e-31: 126: 19.19		HMR1_HUMAN (13-253): 1.95e-91: 275: 19.84
+	Hs
		629193 PD1L1_HUMAN (6-318): 7.26e-35: 133: 16.93		ZA2G_HUMAN (29-219): 4.68e-18: 83.6: 21.88
+	Hs
		1103649 BT2A2_HUMAN (22-291): 1.52e-35: 139: 18.77		HFE_HUMAN (30-223): 1.36e-13: 71.3: 21.54
+	Hs
		545115 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		MICB_HUMAN (31-214): 3.92e-16: 79: 26.46
+	Hs
		182272 TPSN_HUMAN (19-293): 2.7e-33: 132: 18.40		HFE_HUMAN (30-223): 1.36e-13: 71.3: 21.54