HitPredict

Interactor 1: RNF43 (Q68DV7)
E3 ubiquitin-protein ligase RNF43 (EC 2.3.2.27) (RING finger protein 43) (RING-type E3 ubiquitin transferase RNF43)
Gene: RNF43

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35676246
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 449
+	Hs
		933479 RNF43_HUMAN (1-783): 0: 711: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933233 RNF43_HUMAN (1-783): 0: 711: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428255 RNF43_HUMAN (1-783): 0: 711: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1148201 RNF43_HUMAN (1-783): 0: 711: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		933851 RNF43_HUMAN (1-783): 0: 711: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Mm
		610583 CBL_MOUSE (272-682): 5.02e-63: 229: 14.42		TBB5_MOUSE (1-439): 0: 699: 41.00
+	Mm
		610577 CBL_MOUSE (272-682): 5.02e-63: 229: 14.42		TBB4B_MOUSE (1-437): 0: 697: 40.73
+	Hs
		610497 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		610347 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		610443 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428020 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		610348 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		610500 CBL_HUMAN (272-682): 4.13e-48: 185: 14.42		TBB2B_HUMAN (1-440): 0: 697: 40.23