Protein: NOP9
Nucleolar protein 9 (Pumilio domain-containing protein NOP9)

Gene: NOP9
Organism: Saccharomyces cerevisiae S288C
Interactions: 137
UniProt ID: P47077

Gene Ontology (top 5):
GO:0000056 - ribosomal small subunit export from nucleus
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864963

MRD1
Multiple RNA-binding domain-containing protein 1

4

2

Small-scale

0.683

High

864986

NOP56
Nucleolar protein 56

3

1

Small-scale

0.650

High

798255

ENP1
Essential nuclear protein 1

3

1

Small-scale

0.640

High

864987

NOP58
Nucleolar protein 58

3

1

Small-scale

0.633

High

844519

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

Small-scale

0.613

High

692582

NSR1
Nuclear localization sequence-binding protein

2

0

Small-scale

0.585

High

864970

UTP4
U3 small nucleolar RNA-associated protein 4

2

2

Small-scale

0.584

High

864960

RRP5
rRNA biogenesis protein RRP5

2

1

Small-scale

0.571

High

700254

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

0

Small-scale

0.547

High

722059

XPO1
Exportin-1

1

1

High-throughput

0.536

High

816517

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.536

High

864951

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.536

High

864983

SAS10
Something about silencing protein 10

1

0

High-throughput

0.518

High

735268

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.513

High

410214

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

436043

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

441994

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

512526

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513093

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

678415

PWP2
Periodic tryptophan protein 2

1

1

Small-scale

0.479

High

679833

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

738222

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

1

Small-scale

0.479

High

753454

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

754301

DCA13
Protein SOF1

1

1

Small-scale

0.479

High

779137

DHR2
Probable ATP-dependent RNA helicase DHR2

1

1

Small-scale

0.479

High

792124

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

852573

ROK1
ATP-dependent RNA helicase ROK1

1

1

Small-scale

0.479

High

864942

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

864950

UTP17
NET1-associated nuclear protein 1

1

3

Small-scale

0.479

High

864952

HAS1
ATP-dependent RNA helicase HAS1

1

1

Small-scale

0.479

High

864954

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

Small-scale

0.479

High

864956

UTP15
U3 small nucleolar RNA-associated protein 15

1

1

Small-scale

0.479

High

864959

ERB1
Ribosome biogenesis protein ERB1

1

1

Small-scale

0.479

High

864961

UTP13
U3 small nucleolar RNA-associated protein 13

1

3

Small-scale

0.479

High

864962

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

Small-scale

0.479

High

864967

RRP9
Ribosomal RNA-processing protein 9

1

2

Small-scale

0.479

High

864968

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

864971

TSR1
Ribosome biogenesis protein TSR1

1

1

Small-scale

0.479

High

864973

RIX7
Ribosome biogenesis ATPase RIX7

1

1

High-throughput

0.479

High

864979

BMS1
Ribosome biogenesis protein BMS1

1

1

Small-scale

0.479

High

864984

MAK21
Ribosome biogenesis protein MAK21

1

1

Small-scale

0.479

High

704622

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.460

High

149844

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

433722

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

435198

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

455143

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

514712

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

585307

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.458

High

594448

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

666495

DBP2
ATP-dependent RNA helicase DBP2

1

0

Small-scale

0.458

High

670881

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

673199

RRP7
Ribosomal RNA-processing protein 7

1

0

Small-scale

0.458

High

674707

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677467

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

689542

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707514

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735053

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747453

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

751428

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.458

High

778410

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

791070

NOP4
Nucleolar protein 4

1

0

Small-scale

0.458

High

802258

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

806538

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

Small-scale

0.458

High

816857

NUG1
Nuclear GTP-binding protein NUG1

1

0

Small-scale

0.458

High

817591

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

Small-scale

0.458

High

823353

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

Small-scale

0.458

High

836183

DIM1
Dimethyladenosine transferase

1

0

Small-scale

0.458

High

864926

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

Small-scale

0.458

High

864927

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

864928

NOL10
Ribosome biogenesis protein ENP2

1

0

Small-scale

0.458

High

864929

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

864933

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

Small-scale

0.458

High

864934

NSA1
Ribosome biogenesis protein NSA1

1

0

Small-scale

0.458

High

864937

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

864938

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

Small-scale

0.458

High

864939

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

Small-scale

0.458

High

864940

YG5X
Putative methyltransferase YGR283C

1

0

High-throughput

0.458

High

864944

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

864947

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

Small-scale

0.458

High

864948

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

864949

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.458

High

864953

ARX1
Probable metalloprotease ARX1

1

0

Small-scale

0.458

High

864955

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

864958

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

864966

ESF1
Pre-rRNA-processing protein ESF1

1

0

Small-scale

0.458

High

864969

BFR2
Protein BFR2

1

0

Small-scale

0.458

High

864976

SGO1
Shugoshin

1

0

High-throughput

0.458

High

864977

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

864980

FCF2
rRNA-processing protein FCF2

1

0

Small-scale

0.458

High

864988

RRP12
Ribosomal RNA-processing protein 12

1

0

Small-scale

0.458

High

864989

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

427343

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

817897

IMB4
Importin subunit beta-4

1

1

High-throughput

0.445

High

864936

CDH1
APC/C activator protein CDH1

1

1

High-throughput

0.445

High

864964

IMB1
Importin subunit beta-1

1

1

High-throughput

0.445

High

864974

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

430877

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

High-throughput

0.426

High

454525

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.426

High

642417

MCK1
Protein kinase MCK1

1

0

High-throughput

0.426

High

819144

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

825998

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.426

High

864930

NU145
Nucleoporin NUP145

1

0

High-throughput

0.426

High

864931

PSP1
Protein PSP1

1

0

High-throughput

0.426

High

864943

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

864965

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.426

High

864975

MSA1
G1-specific transcription factors activator MSA1

1

0

High-throughput

0.426

High

864981

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.426

High

792740

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

1

High-throughput

0.407

High

805409

BZZ1
Protein BZZ1

1

0

High-throughput

0.282

High

738593

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.279

Low

383778

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

503126

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504294

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

558789

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

579661

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

795434

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

812447

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

864957

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

864972

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

864978

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

358265

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

366722

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.232

Low

367779

ENO1
Enolase 1

1

0

High-throughput

0.232

Low

425135

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.232

Low

452520

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.232

Low

554937

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.232

Low

801072

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.232

Low

816202

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.232

Low

820997

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

0

High-throughput

0.232

Low

825009

TAO3
Cell morphogenesis protein PAG1

1

0

High-throughput

0.232

Low

864932

VPS4
Vacuolar protein sorting-associated protein 4

1

0

High-throughput

0.232

Low

864935

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.232

Low

864941

DMA2
E3 ubiquitin-protein ligase DMA2

1

0

High-throughput

0.232

Low

864945

OSH6
Oxysterol-binding protein homolog 6

1

0

High-throughput

0.232

Low

864946

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.232

Low

864982

SPC3
Signal peptidase complex subunit 3

1

0

High-throughput

0.232

Low

864985

GPR1
G protein-coupled receptor GPR1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025